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Gluten-Free Diet Adherence Evaluation in Adults with Long-Standing Celiac Disease.
Foods
December 2024
Department of Digestive Tract Diseases, Medical University of Lodz, 90-153 Lodz, Poland.
Background: Celiac disease (CD) is an autoimmune disease that results from the interaction of genetic, immune, and environmental factors. According to the 2020 European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines, an elimination diet (i.e.
View Article and Find Full Text PDFThe beneficial effect of adding belimumab in severe and refractory IgA nephropathy: a case report.
Pediatr Nephrol
January 2025
Department of Nephrology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
IgA nephropathy (IgAN) is one of the most common primary glomerular diseases worldwide and is the most common cause of chronic kidney disease (CKD) in China. It lacks recommended treatment in refractory IgAN after conventional therapy. Belimumab, a recombinant human IgG-1λ monoclonal antibody that inhibits the B lymphocyte stimulator, is recommended to treat active lupus nephritis.
View Article and Find Full Text PDFInternational Staging System Status and Trend of Relapse in Multiple Myeloma Cases in a Tertiary Level Health Care.
Mymensingh Med J
January 2025
Dr Md Mahbubul Alam, Junior consultant (Medicine), National Gastroliver Institute and Hospital, Dhaka, Bangladesh; E-mail:
Multiple myeloma (MM) is a haematological neoplasm of mature B-cell lineage origin. It is characterized by abnormal clonal proliferation of plasma cells and presence of monoclonal protein in serum and / or urine. This study was conducted to observe the International Staging System (ISS) status and trends of relapse.
View Article and Find Full Text PDFA case of glucocorticoid-refractory IgA vasculitis with diffuse alveolar hemorrhage: a therapeutic strategy for aberrant immunoglobulin depletion.
Mod Rheumatol Case Rep
December 2024
Department of Rheumatology, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan.
Diffuse alveolar hemorrhage (DAH) is a rare and severe complication of IgA vasculitis (IgAV). Although glucocorticoids and immunosuppressive agents are used for its treatment, there is no consensus on the optimal form of treatment. We herein report the case of a 53-year-old, female patient with IgAV.
View Article and Find Full Text PDFTailored management strategies for IgA nephropathy based on clinical presentations.
Nephrol Dial Transplant
December 2024
Department of Nephrology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina.
The treatment landscape for IgA nephropathy (IgAN) is rapidly evolving with the introduction of novel therapies targeting diverse disease pathways. Some have already been approved in different countries, while others are under investigation in randomized controlled trials (RCTs) with encouraging results. However, almost all performed RCTs have included only patients with refractory non-nephrotic proteinuria and preserved renal function.
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