Objectives: Our study aims to demonstrate the detection of invasion by biparametric prostate MRI (bpMRI).

Materials And Methods: The cases whose histopathological diagnosis was prostate cancer (PCa) and whose mpMRI report was reported as PIRADS 4 and 5 were evaluated retrospectively by two radiologists with different prostate imaging experiences. The images were grouped into two data sets. Dataset-1 was bpMRI, and dataset-2 was mpMRI. Two radiologists first evaluated dataset-1 independently of each other, and 1 month later, dataset-2. They recorded whether there was an invasion and where it was seen in the patients. Then, the results were compared.

Results: A total of 75 patients were included in the study. Periprostatic invasion was detected in 33 of the patients. Both the 1st reader and the 2nd reader image detected all the cases with invasion (100%) separately between dataset-1 and set-2. Compatibility for image dataset-1 and dataset-2 between both readers was observed to be excellent.

Conclusions: There is no need to use contrast agent to evaluate periprostatic invasion and to have an idea about local staging in PCa patients.

Download full-text PDF

Source
http://dx.doi.org/10.24875/CIRU.23000131DOI Listing

Publication Analysis

Top Keywords

periprostatic invasion
12
contrast agent
8
prostate cancer
8
invasion
6
role contrast
4
agent evaluation
4
evaluation periprostatic
4
prostate
4
invasion prostate
4
cancer objectives
4

Similar Publications

Purpose: To identify molecular changes during PCa invasion of adipose space using Spatial Transcriptomic Profiling of PCa cells.

Methods: This study was performed on paired intraprostatic and extraprostatic samples obtained from radical prostatectomy with pT3a pathological stages.

Results: Differential gene expression revealed upregulation of heat shock protein genes: DNAJB1, HSPA8, HSP90AA1, HSPA1B, HSPA1A in PCa PanCK+ cells from the adipose periprostatic space.

View Article and Find Full Text PDF

Ultrasound-guided Transperineal Prostate Thermal Ablation (TPTA) for Benign Prostatic Hyperplasia: Feasibility of an Outpatient Procedure using Radiofrequency Ablation.

Cardiovasc Intervent Radiol

January 2025

Department of Radiology, Universidade Federal de São Paulo (UNIFESP), Rua Dr. Ovidio Pires de Campos, 75, Cerqueira César, São Paulo, SP, 05403-010, Brazil.

Purpose: To evaluate the feasibility, safety, and short-term (3-month) results of transperineal prostate thermal ablation (TPTA) as a minimally invasive outpatient treatment for benign prostatic hyperplasia (BPH).

Materials And Methods: A prospective nonrandomized study of 25 patients with lower urinary tract symptoms secondary to BPH seeking care at 2 interventional radiology centers between March and July 2024. TPTA was performed using a 17G radiofrequency needle with a 10-mm active tip under unconscious sedation combined with bilateral perineal and periprostatic nerve blocks.

View Article and Find Full Text PDF

Background: Prostate cancer (PCa) is a prevalent malignant tumor in males, with a significant incidence of biochemical recurrence (BCR) despite advancements in treatment. Adipose tissue surrounding the prostate, known as periprostatic adipose tissue (PPAT), contributes to PCa invasion through adipocytokine production. However, the relationship between adipocytokine-related genes and PCa prognosis remains understudied.

View Article and Find Full Text PDF

Background: Prostate cancer (PCa) as one of the most prevalent malignancies in men. We introduced a non-invasive quantitative measurement of intraprostatic fat content based on magnetic resonance proton density fat fraction (PDFF) imaging. The study aims to determine the fat fraction (FF) of PCa using proton density magnetic resonance imaging (MRI), gather clinical and routine MRI characteristics, and identify risk factors for high-risk PCa through multifactorial logistic regression.

View Article and Find Full Text PDF

Locally advanced rectal cancer in a young adult affected with dyskeratosis congenita (Zinsser-Cole-Engman syndrome): a case report.

Surg Case Rep

September 2024

Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

Article Synopsis
  • Dyskeratosis congenita (DKC) is a genetic disease characterized by skin pigmentation issues, nail problems, and leukoplakia, with around 8-10% of patients developing cancers, including colorectal cancer.
  • A case study involved a 25-year-old man with DKC who was diagnosed with locally advanced rectal cancer, receiving total neoadjuvant therapy (chemotherapy followed by chemoradiation), which initially reduced the tumor.
  • Despite a near-complete response, the patient experienced tumor regrowth five months later and underwent a total pelvic exenteration surgery, after which he has remained cancer-free for one year.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!