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Extensive gene loss parallels kidney aglomerulism in Syngnathidae. | LitMetric

Extensive gene loss parallels kidney aglomerulism in Syngnathidae.

Curr Biol

Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), and CIMAR Associate Laboratory, University of Porto, 4450-208 Matosinhos, Portugal; Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal. Electronic address:

Published: October 2023

The eccentric seahorses, seadragons, pipehorses and pipefishes (Syngnathidae) have an aglomerular kidney. Here, we show that nephron genes conserved in Bilateria are secondarily eroded/deleted in Syngnathidae genomes. A transcriptome enrichment analysis suggests the predominance of excretion processes in the Syngnathidae kidney. In a lineage where crypsis and idleness are tightly associated, we propose that aglomerulism evolved as an energy-saving strategy.

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http://dx.doi.org/10.1016/j.cub.2023.08.045DOI Listing

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