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Assessing Cancer Knowledge in the General Population of Bisha Province, Saudi Arabia: A Cross-Sectional Study.
Cureus
December 2024
Department of Surgery, College of Medicine, University of Bisha, Bisha, SAU.
Background Cancer is a major cause of morbidity and mortality worldwide. It is anticipated that the number of new cases in Saudi Arabia will increase yearly as a result of significant changes in lifestyle and population development. There is little to no information or studies concerning cancer awareness or knowledge among the residents of Bisha Province.
View Article and Find Full Text PDFKnowledge and Attitudes of Healthcare Professionals Regarding Disabilities in Eastern India.
Cureus
December 2024
General Surgery, All India Institute of Medical Sciences, Deoghar, Deoghar, IND.
Background: Globally, a substantial portion of the population lives with significant disabilities. Despite advancements, individuals with disabilities continue to experience poorer health outcomes, often due to inadequate knowledge and attitudes among healthcare providers. This study aimed to evaluate the knowledge and attitudes of healthcare professionals regarding disabilities in a tertiary care setting.
View Article and Find Full Text PDFThe role of zinc in the premature brain: functions, outcomes and future research perspectives.
Front Pediatr
December 2024
Department of Pediatrics, Division of Neonatology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Zinc (Zn) is one of the most prevalent and essential micronutrients, found in 10% of all human proteins and involved in numerous cellular enzymatic pathways. Zn is important in the neonatal brain, due to its involvement in neurotransmission, synaptic plasticity, and neural signaling. It acts as a neuronal modulator and is highly concentrated in certain brain regions, such as the hippocampus, and the retina.
View Article and Find Full Text PDFUnlabelled: In most cancers, including endometrial cancer, tumor suppressor genes harboring inactivating mutations have been systematically cataloged. However, locus-specific epigenetic alterations contributing to cancer initiation and progression remain only partly described, creating knowledge gaps about functionally significant tumor suppressors and underlying mechanisms associated with their inactivation. Here, we show that PAX2 is an endometrial tumor suppressor recurrently inactivated by a distinct epigenetic reprogramming event not associated with promoter hypermethylation.
View Article and Find Full Text PDFRationale: A scoping review was conducted to investigate knowledge gaps in the informatics research literature regarding sex differences in cognitive decline, identifying existing studies and areas where further studies are needed.
Materials And Methods: We searched Ovid and other databases for studies on sex differences and cognitive decline, focusing on publications in peer-reviewed informatics journals and conference proceedings from 2000 to 2023. The selected manuscripts were analyzed and summarized through discussion among three reviewers.
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