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Mapping curvature domains in human V4 using CBV-sensitive layer-fMRI at 3T.
Front Neurosci
February 2025
York Neuroimaging Centre, University of York, York, United Kingdom.
Introduction: A full understanding of how we see our world remains a fundamental research question in vision neuroscience. While topographic profiling has allowed us to identify different visual areas, the exact functional characteristics and organization of areas up in the visual hierarchy (beyond V1 & V2) is still debated. It is hypothesized that visual area V4 represents a vital intermediate stage of processing spatial and curvature information preceding object recognition.
View Article and Find Full Text PDFAdvancing Nanomedicine Through Electron Microscopy: Insights Into Nanoparticle Cellular Interactions and Biomedical Applications.
Int J Nanomedicine
March 2025
Department of Infection Control, Alzahra General Hospital, Qatif, 31911, Saudi Arabia.
Nanomedicine has revolutionized cancer treatment by the development of nanoparticles (NPs) that offer targeted therapeutic delivery and reduced side effects. NPs research in nanomedicine significantly focuses on understanding their cellular interactions and intracellular mechanisms. A precise understanding of nanoparticle interactions at the subcellular level is crucial for their effective application in cancer therapy.
View Article and Find Full Text PDFAdvances in Starch-Based Nanocomposites for Functional Food Systems: Harnessing AI and Nuclear Magnetic Resonance Technologies for Tailored Stability and Bioactivity.
Foods
February 2025
College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Starch-based nanocomposites (SNCs) are at the forefront of innovations in food science, offering unparalleled opportunities for enhancing the stability, bioactivity, and overall functionality of food systems. This review delves into the potential of SNCs to address contemporary challenges in food formulation, focusing on the synergistic effects of their components. By integrating cutting-edge technologies, such as artificial intelligence (AI) and nuclear magnetic resonance (NMR), we explore new avenues for enhancing the precision, predictability, and functionality of SNCs.
View Article and Find Full Text PDFMass Spectrometry-Based Method for Multiple Allergens Control: Application to Bakery Goods.
Foods
February 2025
Institute of Sciences of Food Production, National Research Council (ISPA-CNR), Via G. Amendola, 122/O, 70126 Bari, Italy.
In recent years, mass spectrometry has played a key role as a confirmatory method to unequivocally identify multiple allergens, increasing the level of protection of allergic consumers. Despite advances made in methods of development, food processing still represents a critical issue in terms of the detection and accurate quantification of allergens due to chemical/structural modifications that can occur on the protein moiety or interferences of matrix compounds that might impair their final detection. Based on the multi-allergen MS/MS method devised within the ThrAll project, in this paper, we investigated the applicability of the developed method for the detection of traces of allergenic ingredients including egg, milk, soy, almond, hazelnut, peanuts, and sesame in two different kind of food matrices, namely cookies and rusks.
View Article and Find Full Text PDFDeciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomics Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment.
Int J Mol Sci
February 2025
Division of Molecular Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to adapt to and exploit their microenvironment for sustained growth. The liver is a common site of metastasis, but the interactions between tumor cells and hepatocytes remain poorly understood. In the context of liver metastasis, these interactions play a crucial role in promoting tumor survival and progression.
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