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Assessing Malignant Risk in B3 Breast Lesions: Clinical Insights and Implications.
J Clin Med
December 2024
Multidisciplinary Breast Centre, Dipartimento Scienze della Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
: B3 breast lesions, characterized by uncertain malignant potential, pose a significant challenge for clinicians. With the increasing use of preoperative biopsies, there is a need for careful management strategies, including watchful waiting, vacuum-assisted excision (VAE), and surgery. This study aims to assess the concordance between preoperative biopsy findings and postoperative histology, with a focus on evaluating the positive predictive value (PPV) for malignancy in B3 lesions.
View Article and Find Full Text PDFDWI in the Differentiation of Malignant and Benign Breast Lesions Presenting with Non-Mass Enhancement on CE-MRI.
Cancers (Basel)
December 2024
Department of Diagnostic and Interventional Radiology, University Hospital Split, Spinčićeva 1, 21000 Split, Croatia.
Article Synopsis
- The study examined if ADC map values of breast lesions with non-mass enhancement on MRI could distinguish between benign and malignant cases.
- A total of 136 patients underwent ultrasound-guided biopsies, and radiologists measured ADC values independently, comparing results to pathology reports.
- The whole tumor region of interest (ROI) showed the highest sensitivity at 91% for detecting benign lesions, while there were no significant ADC value differences between fatty and dense breast tissues.
Clinical feasibility of MRI-guided in-bore prostate biopsies at 0.55T.
Abdom Radiol (NY)
January 2025
University of Michigan, Ann Arbor, USA.
Objective: In-bore MRI-guided biopsy allows direct visualization of suspicious lesions, biopsy needles, and trajectories, allowing accurate sampling when MRI-ultrasound fusion biopsy is not feasible. However, its use has been limited. Wide-bore, lower-field, and lower-cost scanners could help address these issues, but their feasibility for prostate biopsy is unknown.
View Article and Find Full Text PDFTailoring Renal Mass Biopsy: Optimal Core Number and Location Based on Tumor Size for Enhanced Diagnostic Accuracy- A Prospective Ex-Vivo Study.
Urology
January 2025
Urology Department, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:
Objective: To determine the optimal number and location of biopsy cores in renal masses based on mass size in order to maximize diagnostic accuracy.
Methods: This observational study included 360 patients with renal masses, who were divided equally into six groups. Each group was matched in terms of mass size (mass size category: ≤ 4 cm (T1a), 4-7 cm (T1b), 7-10 cm (T2a), and > 10 cm (T2b)).
Insulinoma With Ambiguous Biochemistry, Positive Ga-DOTA-Exendin-4 PET-CT, and Effective Endoscopic Ablation.
JCEM Case Rep
January 2025
Department of Endocrinology, Tan Tock Seng Hospital, Singapore 308433.
A 75-year-old female presented with fasting hypoglycemic episodes. A supervised fast ended at 72 hours fulfilling Whipple triad, with suppressed insulin and C-peptide levels, but discordantly suppressed serum β-hydroxybutyrate levels. After 21 months of recurring symptoms, a repeat fast ended at 48 hours with Whipple triad, suppressed serum β-hydroxybutyrate level, and borderline nonsuppressed C-peptide level, suggesting endogenous hyperinsulinism.
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