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Cholesterol Crystal Embolism Following Mechanical Thrombectomy for Acute Ischemic Stroke.
Cureus
October 2024
Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Cholesterol crystal embolism (CCE) is a rare but serious complication of atherosclerotic plaque rupture, often occurring after endovascular interventions. We report the case of a 73-year-old man who developed CCE following mechanical thrombectomy (MT) for an acute ischemic stroke (AIS) due to left internal carotid artery occlusion. The patient, with a history of hypertension and hyperlipidemia, underwent successful MT with complete recanalization.
View Article and Find Full Text PDFOptogenetic stimulation of the "Zusanli" acupoint alleviates inflammatory pain through active Wnt/β-Catenin and MAPK signaling pathway in rats.
Heliyon
November 2024
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China.
Inflammatory pain, an important form of common pain, negatively influences the quality of life. Pathway-selective optogenetic control is a popular tool in neuronal function research; however, attempts to modulate rodent behavior using pathway-selective optogenetics remain unverified. We developed a methodology for pathway-selective optogenetics in rats, focusing on the delivery of recombinant adeno-associated virus (rAAV) containing channelrhodopsin-2 (ChR2) injected at the "Zusanli" acupoints to the dorsal root ganglia (DRG) and toes, which is a part of the complex neuron network.
View Article and Find Full Text PDFBlue toe syndrome - systemic cholesterol crystal embolism secondary to cardiovascular procedures: a forensic autopsy report of two cases.
Forensic Sci Med Pathol
November 2024
Department of Legal Medicine, Kyorin University School of Medicine, 6- 20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
Blue toe syndrome, also referred to as cholesterol crystal embolism is characterized by the distal embolization of cholesterol crystals originating from ruptured atherosclerotic plaques. This condition commonly arises in the context of cardiovascular procedures. Emboli from the thoracoabdominal aorta primarily affect the downstream extremities and intra-abdominal viscera, often resulting in fatal atheroembolic renal failure.
View Article and Find Full Text PDFA Modular Framework for Task-Agnostic, Energy Shaping Control of Lower Limb Exoskeletons.
IEEE Trans Control Syst Technol
November 2024
Department of Robotics, University of Michigan, Ann Arbor, MI 48109, USA.
Article Synopsis
- Various lower-limb exoskeletons can assist movement for both able-bodied individuals and those with mild to moderate gait disorders, but a universal control system for all activities doesn’t exist.
- The paper introduces a new modular control framework that optimizes joint torques for any exoskeleton configuration in real-time during daily activities like walking, ascending stairs, or transitioning from sitting to standing.
- The study tested this framework on eight able-bodied users with different joint setups, finding that unilateral configurations significantly reduced muscle activation during tasks, while bilateral setups showed minimal effects likely due to weight and design limitations.
Color-induced cognitive conflicts affect muscle activity prior to gait initiation in the Go/No-go task.
Front Hum Neurosci
October 2024
Department of Sensorimotor Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Introduction: In traffic rule, green/blue means go, and red means stop. It has been shown that this prior knowledge about traffic signal colors can affect reaction times (RTs). For example, RTs are longer when responding to a red "Go" signal and withholding the response to a blue "No-go" signal (Red Go/Blue No-go task) than when responding to a blue "Go" signal and withholding the response to a red "No-go" signal (Blue Go/Red No-go task), when responses are provided by button press.
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