Logistics and sourcing management are core in any supply chain operation and are among the critical challenges facing any economy. The specialists classify transport operations and warehouse management as two of the biggest and costliest challenges in logistics and supply chain operations. Therefore, an effective warehouse management system is a legend to the success of timely delivery of products and the reduction of operational costs. The proposed scheme aims to discuss truck unloading operations problems. It focuses on cases where the number of warehouses is limited, and the number of trucks and the truck unloading time need to be manageable or unknown. The contribution of this article is to present a solution that: (i) enhances the efficiency of the supply chain process by reducing the overall time for the truck unloading problem; (ii) presents an intelligent metaheuristic warehouse management solution that uses dispatching rules, randomization, permutation, and iteration methods; (iii) proposes four heuristics to deal with the proposed problem; and (iv) measures the performance of the proposed solution using two uniform distribution classes with 480 trucks' unloading times instances. Our result shows that the best algorithm is , as it has a percentage of 78.7% of the used cases, an average gap of 0.001, and an average running time of 0.0053 s.
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http://dx.doi.org/10.7717/peerj-cs.1582 | DOI Listing |
IJID Reg
March 2025
Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, United Kingdom.
Objectives: Lassa fever (LF) poses a significant health burden in West Africa. The pathophysiology of LF and determinants of clinical spectrum of disease remain poorly understood. We performed a study to understand the correlation of blood inflammatory marker C-reactive protein (CRP), with LF disease severity.
View Article and Find Full Text PDFMitochondria are key regulators of metabolism and ATP supply in skeletal muscle, while circadian rhythms influence many physiological processes. However, whether mitochondrial function is intrinsically regulated in a circadian manner in mouse skeletal muscle is inadequately understood. Accordingly, we measured post-absorptive transcript abundance of markers of mitochondrial biogenesis, dynamics, and metabolism (extensor digitorum longus [EDL], soleus, gastrocnemius), protein abundance of electron transport chain complexes (EDL and soleus), enzymatic activity of SDH (tibialis anterior and plantaris), and maximum uncoupled respiration (tibialis anterior) in different skeletal muscles from female C57BL/6NJ mice at four zeitgeber times (ZT), ZT 1, 7, 13, and 19.
View Article and Find Full Text PDFCureus
December 2024
Department of Pharmacy, Mediclinic Parkview Hospital, Mediclinic Middle East, Dubai, ARE.
Background Drug shortages have become a significant challenge globally, affecting healthcare delivery and patient outcomes. This study aimed to assess drug shortages' prevalence, causes, and impact at a tertiary care hospital in Dubai, the United Arab Emirates (UAE), providing actionable insights for future mitigation strategies. Methods A retrospective descriptive study was conducted at Mediclinic Parkview (MPAR) Hospital, part of Mediclinic Middle East (MCME), UAE.
View Article and Find Full Text PDFDigit Health
January 2025
Ohad Cohen Endocrinology, Tel Hashomer, Israel.
Objective: The objective of this pilot study is to evaluate the feasibility of using an automatic weight management system to follow patients' response to weight reduction medications and to identify early deviations from weight trajectories.
Methods: The pilot study involved 11 participants using Semaglutide for weight management, monitored over a 12-month period. A cloud-based, Wi-Fi-enabled remote weight management system collected and analyzed daily weight data from smart scales.
Heliyon
January 2025
Department of Animal Science, Wolaita Sodo University, P.O.BOX. 138, Wolaita Sodo, Ethiopia.
This review examines the efficiency of live animal and meat value chain from producers to consumers in Ethiopia. Ethiopia has a large livestock population, but the marketing system for live animals and meat remains underdeveloped. Several challenges hinder efficient transactions, including poor infrastructure, illegal cross-border trade, lack of market information, traditional production methods, and absence of grading systems.
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