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http://dx.doi.org/10.1159/000527016DOI Listing

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Per-oral endoscopic myotomy( POEM) is an endoscopic treatment of achalasia. Since the world's first case was performed in Japan in 2008, over 15 years have passed. More than 3,200 cases have been performed at Showa University alone, and over 6,000 cases have been performed throughout Japan.

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Gastroesophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM) has been a limiting factor with POEM. Sling-fiber preservation during POEM was reported to reduce postoperative GERD in Japan. This study investigates the efficacy of this technique in a western population.

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Repeat Peroral Endoscopic Myotomy: Technical Difficulty and Risk Factors.

Gastrointest Endosc

November 2024

Endoscopy Center and Endoscopy Research Institute, Shanghai Collaborative Innovation Center of Endoscopy, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

Background And Aims: Repeat peroral endoscopic myotomy (Re-POEM) appeared to be a promising salvage option for patients with persistent/recurrent symptoms after initial POEM, but it may be more technical challenging. Here we aim to evaluate the safety and technical difficulty of Re-POEM.

Methods: Between July 2012 and October 2023, 158 achalasia patients underwent Re-POEM were retrospectively enrolled.

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Purpose Of Review: The number of hospitalizations for gastroparesis has risen over 300% in recent decades with increased physical, psychological, and healthcare burdens. Gastric per-oral endoscopic myotomy (G-POEM) is a promising therapy for patients with refractory gastroparesis. This article reviews important considerations for G-POEM.

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Advances in Third Space Endoscopy.

Gastroenterol Clin North Am

December 2024

Division of Gastroenterology and Hepatology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA. Electronic address:

Article Synopsis
  • * It discusses peroral endoscopic myotomy (POEM) as a primary treatment for achalasia and compares its outcomes with other treatment options.
  • * The article also covers various other TSE procedures, including G-POEM, Z-POEM, D-POEM, and STER/POET, providing insights for endoscopists looking to improve their knowledge and techniques.
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