AI Article Synopsis
- - Osmotic demyelination syndrome (ODS) can occur in patients with diabetes and low sodium levels (hyponatremia), as shown in a case study involving a 74-year-old man with cirrhosis and uncontrolled type 2 diabetes.
- - The patient developed altered mental status and chorea during treatment for diabetic ketoacidosis (DKA), even without rapid correction of sodium levels or initial MRI changes.
- - Clinicians need to be aware of ODS in DKA patients who exhibit unconsciousness and neurological symptoms, like chorea, and should consider follow-up MRI to detect any later complications.
Article Abstract
Osmotic demyelination syndrome (ODS) occurs in patients with diabetes and hyponatremia. We herein report a case of ODS with chorea detected on serial magnetic resonance imaging (MRI), despite no prompt hyponatremia correction. A 74-year-old man with cirrhosis and uncontrolled type 2 diabetes developed an altered mental status and chorea during treatment for diabetic ketoacidosis (DKA). Despite no rapid sodium correction and normal initial brain MRI findings, serial MRI revealed ODS-related abnormalities. Clinicians should consider ODS in patients with DKA and a hyperosmolar hyperglycemic state displaying unconsciousness and neurological manifestations, including chorea, even without substantial changes in serum sodium levels. An MRI re-examination can help capture missing ODS complications.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11189716 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.2451-23 | DOI Listing |
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