AI Article Synopsis
- Researchers isolated two new compounds from the stem bark of an Annonaceae plant: a prenyl flavanone and a diarylbutanol.
- They also found five known compounds: eriodictyol, quercetin, paprazine, caffeoyltyramine, and feruloyltyramine.
- The new compound demonstrated strong inhibition of -glucosidase, showing a higher potency than the positive control with an IC value of 0.12 M.
Article Abstract
One new prenyl flavanone (), (2)-8-prenyl-5,6-dihydroxy-7-methoxyflavanone, and one new diarylbutanol (), (7')-3'-hydroxy-linderagatin-A, were isolated from the stem bark of (Annonaceae), along with five known compounds, eriodictyol (), quercetin (), paprazine (), --caffeoyltyramine (), and --feruloyltyramine (). Their structures were determined through extensive spectroscopic analyses and comparison with the literature. The -glucosidase inhibitory potential of was evaluated. Compound showed the highest inhibitory activity against -glucosidase and exhibited superior potency compared to the positive control, with an IC value of 0.12 M.
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| http://dx.doi.org/10.1080/14786419.2023.2272024 | DOI Listing |
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