Purpose: To evaluate the shear bond strength of two different resin cements to zirconia after treatment with cold atmospheric pressure plasma (CAPP) and other surface modification methods.

Methods: 189 specimens fabricated from Vita YZ-HT zirconia discs were divided into nine surface treatment groups: (1) Untreated (U), (2) Sandblasting (S), (3) Laser (L), (4) Plasma (P), (5) Primer (PR), (6) Sandblasting + Primer (SPR), (7) Laser + Primer (LPR), (8) Plasma + Primer (PPR), (9) Laser + Plasma + Primer (LPPR). Surface roughness (Ra) and contact angles were measured (n= 10 each), and scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS) analyses were performed (n= 1 each). Specimens were cemented with RelyX Ultimate Clicker adhesive resin cement or Theracem self-adhesive resin cement. The specimens were subjected to shear bond strength (SBS) test. Modes of failure were examined under a stereomicroscope and visualized by SEM.

Results: The S, PR, SPR, PPR and LPPR groups showed significantly greater Ra values than the U group. Significantly lower contact angles were observed in the S, P and L groups versus the U group. The SBS values of SPR, PPR and LPPR groups were significantly greater than those of the U group. CAPP can improve zirconia-resin cement bond strength by increasing the wettability of zirconia surfaces pretreated with the 10-methacryloyloxydecyl dihydrogen phosphate (MDP) primer.

Clinical Significance: The use of cold atmospheric pressure plasma in combination with a primer is a promising clinical procedure for improving resin cement bonding to zirconia surface.

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