A 78-year-old woman with hypertrophic cardiomyopathy underwent a septal myomectomy and valve replacement. In the immediate postoperative period she developed shock of mixed etiology and died. At autopsy, hepatomegaly and splenomegaly were identified, with PAS and Giemsa positive intracellular ceroid granular deposits. Sea-blue histiocytosis is an extremely rare, chronic and benign deposit disease. It is characterized by hepatosplenomegaly, thrombocytopenia and lymphadenopathy. The presence of ceroid substance in granules in PAS and Giemsa stains should establish the diagnosis of suspicion.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.annpat.2023.10.001 | DOI Listing |
Publication Analysis
Top Keywords
sea-blue histiocytosis
8
pas giemsa
8
histiocytosis 78-year-old
4
78-year-old woman
4
woman hypertrophic
4
hypertrophic cardiomyopathy
4
cardiomyopathy underwent
4
underwent septal
4
septal myomectomy
4
myomectomy valve
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!