The effects of alpha and beta adrenoreceptors blockade and surgical kidney denervation on ultradian rhythmicity in urine excretion were investigated in four dogs. Pharmacological treatments and surgical denervation of the kidneys suppressed the ultradian rhythmicity in urine flow but did not completely eliminate the ultradian rhythms in urinary osmolality and in electrolyte concentrations. These findings suggest that the autonomic nervous system plays a major role in the regulation of the ultradian rhythms in water excretion in dogs. The partial persistence of ultradian rhythms in urine osmolality and electrolyte concentrations after autonomic denervation supports the assertion that the ultradian rhythms in solute concentrations are regulated by different mechanisms to those of water excretion, suggesting the possible involvement of a multioscillatory system.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0031-9384(86)90099-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Circadian clockwork controls the balance between mitochondrial turnover and dynamics: What is life … without time marking?
Biochim Biophys Acta Bioenerg
January 2025
Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy. Electronic address:
Circadian rhythms driven by biological clocks regulate physiological processes in all living organisms by anticipating daily geophysical changes, thus enhancing environmental adaptation. Time-resolved serial multi-omic analyses in vivo, ex vivo, and in synchronized cell cultures have revealed rhythmic changes in the transcriptome, proteome, and metabolome, involving up to 50 % of the mammalian genome. Mitochondrial oxidative metabolism is central to cellular bioenergetics, and many nuclear genes encoding mitochondrial proteins exhibit both circadian and ultradian oscillatory expression.
View Article and Find Full Text PDFChallenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics.
NPJ Biol Timing Sleep
January 2025
Section of Chronobiology, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH UK.
Time-of-day variation in the molecular profile of biofluids and tissues is a well-described phenomenon, but-especially for proteomics-is rarely considered in terms of the challenges this presents to reproducible biomarker identification. We provide a case study analysis of human circadian and ultradian rhythmicity in proteins, including in the complement and coagulation cascades and apolipoproteins, with PLG, CFAH, ZA2G and ITIH2 demonstrated as rhythmic for the first time. We also show that rhythmicity increases the risk of Type II errors due to the reduction in statistical power from increased variance, and that controlling for rhythmic time-of-day variation improves statistical power and reduces the chances of Type II errors.
View Article and Find Full Text PDFTwelve-hour ultradian rhythmic reprogramming of gene expression in the human ovary during aging.
J Assist Reprod Genet
January 2025
Center of Reproductive Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Background: The 12-h ultradian rhythm plays a crucial role in metabolic homeostasis, but its role in ovarian aging has not been explored. This study investigates age-related changes in 12-h rhythmic gene expression across various human tissues, with a particular focus on the ovary.
Methods: We analyzed transcriptomic data from the GTEx project to examine 12-h ultradian rhythmic gene expression across multiple peripheral human tissues, exploring sex-specific patterns and age-related reprogramming of both 12-h and 24-h rhythmic gene expression.
A Longitudinal Study on Parent-Infant Rest-Activity Rhythms Using Actigraphy From Late Pregnancy to Eight Months After Birth.
Cureus
December 2024
Nursing, Tokyo Women's Medical University, Tokyo, JPN.
Circadian rhythms develop from an ultradian to a circadian rhythm during a few months in the early human life stage. One of the strong factors in promoting the development of circadian rhythms during infancy is maternal rest-activity rhythms. However, few studies have examined comparing the rest-activity rhythms of parents and infants.
View Article and Find Full Text PDFRe-scoping ultradian rhythms in the context of metabolism.
Front Physiol
December 2024
Energy and Sustainability Research Institute Groningen, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, Netherlands.
Rapid, ultradian biological rhythms are only partly comparable to circadian (24-h) rhythms. Often, the ensuing expectations from this comparison are that 1) ultradian rhythms should be driven by discrete oscillators, 2) they are biochemically buffered, and 3) they must be functionally linked to extrinsic events and cycles. These three expectations are not always met, but perhaps there is an adaptive benefit to ultradian rhythms not meeting these expectations, which sets them functionally apart from circadian rhythms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!