Background And Objective: The Internet of medical things is enhancing smart healthcare services using physical wearable sensor-based devices connected to the Internet. Machine learning techniques play an important role in the core of these services for remotely consulting patients thanks to the pattern recognition from on-device data, which is transferred to the central servers from local devices. However, transferring personally identifiable information data to servers could become a source for hackers to steal from, manipulate and perform illegal activities. Federated learning is a new branch of machine learning that creates directly training models from on-device data and aggregates these learned models on the servers without centralized data. Another way to protect data confidentiality on computer systems is data encryption. Data encryption transforms data into another form that only users with authority to a decryption key can read. In this work, we propose a novel method enabling preservation of client privacy and protection of client biomedical data from illegal hackers while transmitting through the Internet.
Methods: We propose a method applying 3-dimensional convolutional neural networks for human activity recognition using multiple sensory data. In order to protect the data, we apply the bitwise XOR operator encryption technique. Then, we extend our 3-dimensional convolutional neural network methods to both traditional federated learning and the federated learning based on multi-key homomorphic encryption using the proposed encrypting data.
Results: Based on leave-one-out-cross-validation, the 3-dimensional method obtains an accuracy of 94.6% and of 94.9% (without data encrypting and without federated learning) tested on two different benchmarked datasets, Sport and DaLiAC respectively. Accuracy is decreased slightly to 89.5% (from 94.6% of the baseline) when we use the proposed encrypting data method. However, the encryption-data-based method still has a potential result compared to the state-of-the-art which only uses raw data. In addition, the proposed full federated learning scheme of this work shows that illegal persons who somehow can get the trained model transmitted via networks cannot infer the private result.
Conclusions: This novel method for sensory data representation which translates temporal and frequency bio-signal values to voxel intensities that can encode 3-dimensional activity images. Secondly, the proposed 3-dimensional convolutional neural network methods outperform other deep-learning-based human activity recognition approaches. Finally, extensive experiments show the proposed data-encrypted federated learning approach can achieve feasibility in terms of efficiency in privacy preservation.
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http://dx.doi.org/10.1016/j.cmpb.2023.107854 | DOI Listing |
Background: Population aging and the increase in memory-related diseases have motivated the search for accessible cognitive screening instruments. To develop a digital memory and learning test (DMLT) based on Rey's Auditory Verbal Learning Test (RAVLT) principles to assess cognition in the elderly and identify early cognitive decline.
Methods: The research was divided into two phases: developing the digital test and the experimental phase of comparison with a reference test.
Purpose Of Review: This review aims to evaluate the impact of artificial intelligence (AI) on cancer health equity, specifically investigating whether AI is addressing or widening disparities in cancer outcomes.
Recent Findings: Recent studies demonstrate significant advancements in AI, such as deep learning for cancer diagnosis and predictive analytics for personalized treatment, showing potential for improved precision in care. However, concerns persist about the performance of AI tools across diverse populations due to biased training data.
Cancer Cell
December 2024
Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA. Electronic address:
Molecular subtypes, such as defined by The Cancer Genome Atlas (TCGA), delineate a cancer's underlying biology, bringing hope to inform a patient's prognosis and treatment plan. However, most approaches used in the discovery of subtypes are not suitable for assigning subtype labels to new cancer specimens from other studies or clinical trials. Here, we address this barrier by applying five different machine learning approaches to multi-omic data from 8,791 TCGA tumor samples comprising 106 subtypes from 26 different cancer cohorts to build models based upon small numbers of features that can classify new samples into previously defined TCGA molecular subtypes-a step toward molecular subtype application in the clinic.
View Article and Find Full Text PDFComput Biol Med
January 2025
Health Innovation and Transformation Centre, Federation University, Victoria, 3842, Australia; BioThink, Queensland, 4020, Australia.
Reconstruction of Gene Regulatory Networks (GRNs) is essential for understanding gene interactions, their impact on cellular processes, and manifestation of diseases, including drug discovery. Among various mathematical and dynamic models used for GRN reconstruction, S-system model, comprising non-linear differential equations, is widely utilised to capture the behaviour of complex biological systems with non-linear and time-dependent interactions. However, as the network size increases, computational demand for network inference grows due to a greater number of estimation parameters, significantly impacting the performance of optimisation algorithms.
View Article and Find Full Text PDFPLoS One
January 2025
Portugal Football School, Portuguese Football Federation, Oeiras, Portugal.
This study aimed to investigate the impact of different offensive-reward-related rules on the physical performance, perceived exertion and enjoyment of young basketball players during small-sided games (SSG). Eighteen youth male players (age: 13.3±0.
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