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Acupuncture or moxibustion adjuvant chemotherapy for advanced non-small cell lung cancer: Systematic review and network meta-analysis. | LitMetric

AI Article Synopsis

  • * Researchers analyzed data from 14 randomized controlled trials with 921 patients, finding that acupuncture combined with chemotherapy significantly improved outcomes compared to chemotherapy alone.
  • * Results indicated that the combined approach not only enhanced cancer treatment effectiveness but also improved patient safety, suggesting it as the optimal strategy for NSCLC treatment.

Article Abstract

Background: To compare the advantages and disadvantages of different acupuncture and moxibustion methods by network meta-analysis, in order to find out the best acupuncture and moxibustion adjuvant chemotherapy scheme of non-small cell lung cancer (NSCLC).

Methods: Randomized controlled trials of acupuncture and moxibustion adjuvant chemotherapy in the treatment of NSCLC were searched in PubMed, Cochrane Library, Web of science, EMbase, China National Knowledge Infrastructure, Wanfang, VIP database and SinoMed. The retrieval time was up to December 03, 2022. ROB2 was used to evaluate publication bias, and Stata16 was used for network meta-analysis.

Results: A total of 14 studies involving 921 patients were included. The results of network Meta-analysis showed that the effect of acupuncture combined with chemotherapy was better than that of chemotherapy (RR = 1.28, 95%CI (1.04,1.58), P < .0001). The effect of acupuncture combined with chemotherapy was better than that of chemotherapy in improving KPS score (MD = 9.01, 95%CI (3.35,14.67), P < .0001). The safety of acupuncture combined with chemotherapy (RR = 0.35, 95%CI (0.15,0.83), P < .0001) was better than that of chemotherapy.

Conclusion: Acupuncture combined with chemotherapy has the best comprehensive effect.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589565PMC
http://dx.doi.org/10.1097/MD.0000000000035000DOI Listing

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