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Knowledge claims.
Adv Health Sci Educ Theory Pract
March 2025
Department of Community Health Sciences and Office of Health and Medical Education Scholarship, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
In this editorial the editor considers the nature and use of knowledge claims in the sciences of health professions education, and she explores ways in which these knowledge claims can be expressed and parsed that speak to their veracity, authority, and reliability.
View Article and Find Full Text PDFRisks to the clinician of risk management: recalled and anticipated consequences of decision-making.
Front Psychiatry
February 2025
Cheshire and Wirral Partnership NHS Foundation Trust, Chester, United Kingdom.
Background: Despite extensive literature studying how we make decisions in the face of uncertainty, the empirical study of real-world clinical decision-making in mental health practice remains limited. Decisions in clinical settings are not just made on the basis of clinical factors. A key non-clinical influence on decision making is the clinician's concerns about the 'threat' to themselves from a future adverse incident and the subsequent retrospective scrutiny of their decision-making.
View Article and Find Full Text PDFChild and adolescent mental health therapists' use of family-based treatment for adolescent restrictive eating disorders.
Eat Disord
March 2025
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
In order to identify factors that may impede youth access to evidence-based treatment, the current study examined child and adolescent mental health therapists' use of Family-Based Treatment (FBT) and other psychotherapeutic approaches to treat adolescents with restrictive eating disorders. A sample of 91 therapists from a variety of backgrounds (e.g.
View Article and Find Full Text PDFExpansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants.
J Am Chem Soc
March 2025
Centre of Biomolecular Drug Research, Leibniz University Hannover, Schneiderberg 38, Hannover 30167, Germany.
Triterpenoids and steroids are structurally complex polycyclic natural products with potent biological functions, for example, as hormones. In all eukaryotes, the carbon skeletons of these compounds are generated by oxidosqualene cyclases, which carry out a polycyclization cascade to generate four or five rings with up to nine stereogenic centers in a targeted manner. The tight stereochemical control of this cascade reaction severely limits the stereochemical space accessible by known oxidosqualene cyclases.
View Article and Find Full Text PDFMapping Children's Social and Motor Skill Profiles to Autistic Traits and Behavioral Tendencies.
J Autism Dev Disord
March 2025
Department of Psychology, Western University, 1151 Richmond St, London, ON, N6A3K7, Canada.
We used a person-centered approach to: (1) elucidate distinct configurations of social and motor skills across subgroups of children, (2) determine how profiles map to autistic traits and behavioral tendencies, and (3) identify how children with and without different diagnoses are categorized within profiles. Parents/guardians (N = 538) of 5- to 15-year-olds reported on their children's autistic traits, social skills, motor skills, and behavioral tendencies. Factor scores were extracted as indicators for latent profile analysis and a series of profile solutions were generated.
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