Problem: Myocardial infarction (MI) is a classic cardiovascular disease (CVD) that requires prompt diagnosis. However, due to the complexity of its pathology, it is difficult for cardiologists to make an accurate diagnosis in a short period.
Aim: In the clinical, MI can be detected and located by the morphological changes on a 12-lead electrocardiogram (ECG). Therefore, we need to develop an automatic, high-performance, and easily scalable algorithm for MI detection and location using 12-lead ECGs to effectively reduce the burden on cardiologists.
Methods: This paper proposes a multi-task channel attention network (MCA-net) for MI detection and location using 12-lead ECGs. It employs a channel attention network based on a residual structure to efficiently capture and integrate features from different leads. On top of this, a multi-task framework is used to additionally introduce the shared and complementary information between MI detection and location tasks to further enhance the model performance.
Results: Our method is evaluated on two datasets (The PTB and PTBXL datasets). It achieved more than 90% accuracy for MI detection task on both datasets. For MI location tasks, we achieved 68.90% and 49.18% accuracy on the PTB dataset, respectively. And on the PTBXL dataset, we achieved more than 80% accuracy.
Conclusion: Numerous comparison experiments demonstrate that MCA-net outperforms the state-of-the-art methods and has a better generalization. Therefore, it can effectively assist cardiologists to detect and locate MI and has important implications for the early diagnosis of MI and patient prognosis.
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http://dx.doi.org/10.1016/j.compbiomed.2022.106199 | DOI Listing |
Alzheimers Dement
December 2024
Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, North Holland, Netherlands.
The lack of an in-vivo pathology marker for synuclein pathology has been a long standing challenge for dementia for Lewy bodies (DLB) research. This issue is critically important for phase II trials, which are often small, requiring the precise measurement of the biological effects, whether disease modifying or symptomatic. Recent advances have enabled the determination of alpha-synuclein pathology status with CSF measurements, using aggregation assays [RT-QUIC].
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, San Francisco, San Francisco, CA, USA.
Background: Cognitive assessment should be actively incorporated into the clinical evaluation of patients in Primary Health Care (PHC) settings. This is because of the imminent demand with the changing demographics especially in low- and middle-income countries (LMICs) concerning dementia and Alzheimer's disease.
Method: A cross-sectional mixed-method descriptive study was conducted to evaluate the useability and performance of a tablet-based cognitive assessment tool (TabCAT) for use in geriatric primary healthcare settings in southeast Nigeria.
Can Vet J
January 2025
Neurology Unit, Centre Hospitalier Vétérinaire Anicura Pommery, 226 Boulevard Pommery, 51100 Reims, France.
A 4-year-old neutered female domestic shorthair indoor cat was presented with sudden onset of abnormal and painful tail-carriage. The tail was held horizontally for the first centimeters from the base and a flaccid paralysis was evident more distally. Magnetic resonance imaging of the lumbosacral spine and tail revealed a lesion located in the right and muscles along the 1st coccygeal vertebrae.
View Article and Find Full Text PDFJ Rural Med
January 2025
DeepTek Medical Imaging Pvt. Ltd., India.
Objective: To evaluate the performance of Genki, a computer-aided detection (CADe) software, in detecting tuberculosis (TB) using chest radiography in a mobile TB screening program in Chennai, India.
Materials And Methods: Genki, an AI-based CADe software, was employed in four mobile diagnostic units in remote areas of Chennai, India for screening TB. Patients from remote areas of Chennai who visited the vans and registered in the screening program underwent chest radiography, and the acquired X-ray scans were analyzed using Genki, which provided an assessment of each scan as either "TB suggestive" or "TB not suggestive".
Sheng Li Xue Bao
December 2024
Department of Physiology, Zhuhai Campus of Zunyi Medical University, Zhuhai 519040, China.
The aim of this study was to conduct experiments using laser speckle contrast imaging (LSCI) technology to investigate the effects of high salt diet on renal vascular reactivity in mice. LSCI is a technology for monitoring blood flow based on the laser speckle principle. It has been widely used to detect microcirculatory functions in tissues such as the skin and brain.
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