Background: Ethylene and vinyl acetate (EVA) and polyether block amide (PEBA) are recently the most widely used materials for advanced footwear technology (AFT) that has been shown to improve running economy (RE). This study investigated the effects of these midsole materials on RE and biomechanics, in both fresh and worn state (after 450 km).
Methods: Twenty-two male trained runners participated in this study. Subjects ran four 4-min trials at 13 km‧h with both fresh EVA and PEBA AFT and with the same models with 450 km of wear using a randomized crossover experimental design. We measured energy cost of running (W/kg), spatiotemporal, and neuromuscular parameters.
Results: There were significant differences in RE between conditions (p = 0.01; n = 0.17). There was a significant increase in energy cost in the worn PEBA condition compared with new (15.21 ± 1.01 and 14.87 ± 0.99 W/kg; p < 0.05; ES = 0.54), without differences between worn EVA (15.13 ± 1.14 W/kg; p > 0.05), and new EVA (15.15 ± 1.13 w/kg; ES = 0.02). The increase in energy cost between new and worn was significantly higher for the PEBA shoes (0.32 ± 0.38 W/kg) but without significant increase for the EVA shoes (0.06 ± 0.58 W/kg) (p < 0.01; ES = 0.51) with changes in step frequency and step length. The new PEBA shoes had lower energy cost than the new EVA shoes (p < 0.05; ES = 0.27) with significant differences between conditions in contact time.
Conclusion: There is a clear RE advantage of incorporating PEBA versus EVA in an AFT when the models are new. However, after 450 km of use, the PEBA and EVA shoes had similar RE.
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http://dx.doi.org/10.1111/sms.14526 | DOI Listing |
Pharmaceutics
January 2025
School of Pharmacy, Changzhou University, Changzhou 213164, China.
Non-viral vectors have gained recognition for their ability to enhance the safety of gene delivery processes. Among these, polyethyleneimine (PEI) stands out as the most widely utilized cationic polymer due to its accessibility. Traditional methods of modifying PEI, such as ligand conjugation, chemical derivatization, and cross-linking, are associated with intricate preparation procedures, limited transfection efficiency, and suboptimal biocompatibility.
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January 2025
Division of Human Nutrition and Health, Wageningen University & Research, 6700 AB Wageningen, The Netherlands.
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Polymers (Basel)
January 2025
School of Chemical Engineering, Yeungnam University, 280 Daehak-ro, Gyeongsan 38541, Republic of Korea.
Solid polymer electrolytes (SPEs) for symmetrical supercapacitors are proposed herein with activated carbon as electrodes and optimized solid polymer electrolyte membranes, which serve as the separators and electrolytes. We propose the design of a low-cost solid polymer electrolyte consisting of guanidinium nitrate (GuN) and poly(ethylene oxide) (PEO) with poly(vinylpyrrolidone) (PVP). Using the solution casting approach, blended polymer electrolytes with varying GuN weight percentage ratios of PVP and PEO are prepared.
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January 2025
Instituto de Investigaciones en Físico-Química de Córdoba (INFIQC), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba 5000, Argentina.
Lithium-sulfur (Li-S) batteries are promising candidates for next-generation energy storage due to their high energy density, cost-effectiveness, and environmental friendliness. However, their commercialization is hindered by challenges, such as the polysulfide shuttle effect, lithium dendrite growth, and low electrical conductivity of sulfur cathodes. Cellulose, a natural, renewable, and versatile biopolymer, has emerged as a multifunctional material to address these issues.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
Department of Biomedical Engineering, School of Engineering Sciences, College of Basic & Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 77, Ghana.
: Pteridine reductase 1 (PTR1) has been one of the prime targets for discovering novel antileishmanial therapeutics in the fight against Leishmaniasis. This enzyme catalyzes the NADPH-dependent reduction of pterins to their tetrahydro forms. While chemotherapy remains the primary treatment, its effectiveness is constrained by drug resistance, unfavorable side effects, and substantial associated costs.
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