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Primary care management of mild cognitive impairment in a stroke survivor: A case report on facilitating return to work.
Malays Fam Physician
December 2024
MD, MMed (Family Medicine), MPhil, Department of Family Medicine, Medical Faculty, Hospital Canselor Tuanku Muhriz (HCTM), National University of Malaysia (UKM), Kuala Lumpur, Malaysia.
This case report delves into facilitating return to work (RTW) in a working-age stroke survivor. The patient was a 42-year-old Malay man who experienced multifocal lacunar infarctions in April 2022. He demonstrated substantial motor function recovery but presented with subtle cognitive deficits impacting various domains.
View Article and Find Full Text PDFComplement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes.
J Neuroinflammation
January 2025
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Following recent advances in post-thrombectomy stroke care, the role of neuroinflammation and neuroprotective strategies in mitigating secondary injury has gained prominence. Yet, while neuroprotection and anti-inflammatory agents have re-emerged in clinical trials, their success has been limited. The neuroinflammatory response in cerebral ischemia is robust and multifactorial, complicating therapeutic approaches targeting single pathways.
View Article and Find Full Text PDFPersonalized whole-brain activity patterns predict human corticospinal tract activation in real-time.
Brain Stimul
December 2024
Movement and Cognitive Rehabilitation Science Program, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX, USA. Electronic address:
Background: Transcranial magnetic stimulation (TMS) interventions could feasibly treat stroke-related motor impairments, but their effects are highly variable. Brain state-dependent TMS approaches are a promising solution to this problem, but inter-individual variation in lesion location and oscillatory dynamics can make translating them to the poststroke brain challenging. Personalized brain state-dependent approaches specifically designed to address these challenges are needed.
View Article and Find Full Text PDFMultifactorial interplay on language recovery following left-hemispheric stroke: A retrospective study.
J Neuropsychol
December 2024
CNRS, LPNC, Université Grenoble Alpes, Université Savoie Mont Blanc, Grenoble, France.
Understanding the relative contribution of various factors influencing initial severity of aphasia and recovery after a stroke is essential for optimising neurorehabilitation programmes. We investigated how various significant sociodemographic, cognitive, clinical, stroke-related and rehabilitation-related factors modulate aphasia severity and language recovery following left-hemispheric stroke. Employing an innovative method, we conducted a retrospective analysis of 96 stroke participants to explore the combined impact of these factors.
View Article and Find Full Text PDFMotivation in veterans with an acute/subacute ischemic stroke did not improve cognition and functional motor recovery but reduced deaths.
Eur J Phys Rehabil Med
December 2024
Veterans Affairs Medical Center, Oklahoma City, OK, USA.
Background: The role of motivation per se in the presence or absence of depression in stroke-related cognitive and functional motor recovery has not been studied.
Aim: This study aimed to determine the role of motivation on cognition and functional motor recovery in patients after an acute and subacute ischemic stroke.
Design: Prospective, observational, single-center study.
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