The epidemiology of parkinsonism was systematically studied in details in Sofia, a city of 1,167,295 inhabitants. The critical date of the study was the 31st of December, 1983. During the period of 10 years from 1972 to 1982 the morbidity of parkinsonism was 165.85/100,000 inhabitants, with a slight excess of men over women (52.1:47.9%); the average age was 60 years. A vascular etiology of parkinsonism was considered in 44%, followed by degenerative (32.55%), postencephalitic (19%), traumatic (2.4%), and toxic etiology (1.7%). The mixed clinical form of the syndrome was met most frequently (46.6%), followed by predominantly the tremor form (35.45%), predominantly the rigid form (16.8%) and the bradykinetic form (1.15%). There was a greater prevalence of the mild degree of severity of the disease (62.3%), followed by the marked degree (20.9%) and the moderate degree (16.8%). Parkinsonian patients in Bulgaria without exception receive medication and all other kinds of treatment free of charge.
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http://dx.doi.org/10.1159/000110826 | DOI Listing |
JAMA Netw Open
January 2025
Department of Medicine, University of California, San Francisco.
Importance: Multiple organ dysfunction (MOD) is a leading cause of in-hospital child mortality. For survivors, posthospitalization health care resource use and costs are unknown.
Objective: To evaluate longitudinal health care resource use and costs after hospitalization with MOD in infants (aged <1 year) and children (aged 1-18 years).
JAMA Netw Open
January 2025
Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California.
Importance: Limited research explores mental health disparities between individuals in sexual and gender minority (SGM) populations and cisgender heterosexual (non-SGM) populations using national-level data.
Objective: To explore mental health disparities between SGM and non-SGM populations across sexual orientation, sex assigned at birth, and gender identity within the All of Us Research Program.
Design, Setting, And Participants: This cross-sectional study used survey data and linked electronic health records of eligible All of Us Research Program participants from May 31, 2017, to June 30, 2022.
JAMA Netw Open
January 2025
Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota.
Importance: There is a clear benefit to body armor against firearms; however, it remains unclear how these vests may influence day-to-day patient encounters when worn by emergency medical services (EMS).
Objective: To determine the association of ballistic vests worn by EMS clinicians with workplace violence (WPV) and disparities in care among racial and/or ethnic minority patients.
Design, Setting, And Participants: Prospective cohort study of a volunteer-based sample of EMS clinicians at a large, multistate EMS agency encompassing 15 ground sites across the Midwest from April 1, 2023, to March 31, 2024.
JAMA Netw Open
January 2025
Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Importance: Obesity, a chronic disease with escalating global prevalence, poses considerable health risks. Glucagon-like peptide 1 receptor agonists (GLP-1RAs), including liraglutide, semaglutide, and tirzepatide, have demonstrated efficacy for weight loss in clinical trials. The paradigm shift in the approach to obesity management drugs (OMDs) may offer an opportunity to examine online search activity and prescription trends.
View Article and Find Full Text PDFAging Clin Exp Res
January 2025
Department of Anesthesiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610000, Sichuan, China.
Objective: The primary goal was to investigate whether the presence of preoperative lacunar infarcts (LACI) was associated with postoperative delirium (POD) in elderly patients undergoing elective major abdominal surgery.
Design: A prospective cohort study.
Setting And Participants: Patients aged ≥ 65 years from a tertiary level A hospital in China.
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