MXenes have garnered research attention in the field of biomedical applications due to their unique properties, such as a large surface area, low toxicity, biocompatibility, and stability. Their optical behavior makes them versatile for a wide range of biomedical applications, from diagnostics to therapeutics. Nonetheless, MXenes have some minor limitations, including issues with restacking, susceptibility to oxidation, and a non-semiconducting nature. These limitations have prompted researchers to explore the incorporation of metal oxides into MXene structures. Metal oxides possess advantageous properties such as a high surface area, biocompatibility, intriguing redox behavior, catalytic activity, semiconducting properties, and enhanced stability. Incorporating metal oxides into MXenes can significantly improve their conductivity, surface area, and mechanical strength. In this review, we emphasize the importance of incorporating metal oxides into MXenes for light-influenced biomedical applications. We also provide insights into various preparation methods for incorporating metal oxides into MXene structures. Furthermore, we discuss how the incorporation of metal oxides enhances the optical behavior of MXenes. Finally, we offer a glimpse into the future potential of metal oxide-incorporated MXenes for diverse biomedical applications.
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