During spaceflight, it is important to consider the mechanisms by which surgeries and medical procedures can be safely and efficiently conducted. Instruments used to carry out these processes need to be sterilized. Thus, we have designed and tested a three-dimensional-printed (3D-printed) portable sterilizer that implements far ultraviolet-C (Far UV-C) light radiation to disinfect bacteria and microorganisms from surgical instruments. The sterilizer was 3D-printed with polylactic acid filament. Effectiveness was assessed through three trials at differing times of sterilization and compared against a control group of no sterilization and against Clorox wipes. Cultures were incubated on agar dishes and counted with ImageJ. Increasing time under Far UV-C light radiation increased the percentage of sterilization up to 100% at 10 min. The 3D-printed sterilizer was significantly better than Clorox wipes and control. As sterilization will be necessary for surgical procedures in microgravity and upmass is a significant concern, we have successfully demonstrated a 3D-printable portable sterilizer for surgical instruments that achieves 100% success in using Far UV-C light to disinfect its surface of bacteria with a 10-min sterilizing time. Further research is necessary to test this design in microgravity and with differently sized and shaped instruments.
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http://dx.doi.org/10.3357/AMHP.6294.2023 | DOI Listing |
Infect Control Hosp Epidemiol
January 2025
Department of Internal Medicine, Baystate Medical Center, Springfield, MA, USA.
A citywide boil water notice necessitated an alternative solution for treating contaminated water. We report our experience using portable reverse osmosis machines to treat the municipal water to provide purified water to patient care areas where non-sterile water was needed, preventing interruptions in services like elective surgeries.
View Article and Find Full Text PDFJ Insect Sci
January 2025
Northern Research Station, U.S. Forest Service, United States Department of Agriculture, Hamden, CT, USA.
Asian longhorned beetle (Anoplophora glabripennis Motschulsky), a wood borer (Coleoptera: Cerambycidae) native to China, has been unintentionally and repeatedly introduced to North American and European landscapes as a stow-away in the wood packing material commonly used in international trade. Asian longhorned beetle causes extensive damage and mortality in multiple deciduous tree species and in response, countries in both North America and Europe have adopted policies of eradication. Models that integrate patterns of Asian longhorned beetle dispersal with records of infested trees are critical in optimizing survey and eradication efforts and tracking eradication progress.
View Article and Find Full Text PDFAntibiotics (Basel)
November 2024
Department of Infectious Diseases and Laboratory Medicine, Kanazawa University, Kanazawa 920-8641, Japan.
: In environments with high-frequency contact surfaces, drug-resistant bacteria, such as carbapenem-resistant and methicillin-resistant (MRSA), can survive for extended periods, contributing to healthcare-associated infections. Ultraviolet (UV)-C irradiation often fails to adequately disinfect shadowed areas, leading to a persistent contamination risk. We evaluated the effectiveness of using a UV-C containment unit (UVCCU) in conjunction with UV-C irradiation to improve the sterilization effects on both direct and indirect surfaces, including shadowed areas, and to assess the leakage of UV radiation to the surroundings.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Respiratory interventions including noninvasive ventilation, continuous positive airway pressure and high-flow nasal oxygen generated infectious aerosols may increase risk of airborne disease (SARS-CoV-2, influenza virus) transmission to healthcare workers. We developed and tested a prototype portable UV-C device to sterilize high flows of viral-contaminated air from a simulated patient source at airflow rates of up to 100 l/m. Our device consisted of a central quartz tube surrounded 6 high-output UV-C lamps, within a larger cylinder allowing recirculation past the UV-C lamps a second time before exiting the device.
View Article and Find Full Text PDFSci Rep
December 2024
Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32611, USA.
This paper introduces a novel, compact plasma sterilization system, the Active Plasma Sterilizer (APS), for planetary protection space missions. The development of the APS system is done through iterative testing and design modifications aimed at addressing decontamination modalities for time and temperature, cleaning adhesive surfaces, and cleaning protocols beyond alcohol and bleach. Decontamination testing of Deinococcus radiodurans, Geobacillus stearothermophilus (spore forming bacteria), and Aspergillus fumigatus (fungi) was verified for the APS on relevant materials of 4 to 5 log reduction up to complete killing in 45 min or less.
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