Many cities have long suffered from the events of fine particulate matter (PM) pollutions. The Taiwanese Government has long strived to accurately predict the short-term hourly concentration of PM for the warnings on air pollution. Long Short-Term Memory neural network (LSTM) based on deep learning improves the prediction accuracy of daily PM concentration but PM prediction for next hours still needs to be improved. Therefore, this study proposes innovative Application-Strategy-based LSTM (ASLSTM) to accurately predict the short-term hourly PM concentrations, especially for the high PM predictions. First, this study identified better spatiotemporal input feature of a LSTM for obtaining this Better LSTM (BLSTM). In doing so, BLSTM trained by appropriate datasets could accurately predict the next hourly pollution concentration. Next, the application strategy was applied on BLSTM to construct ASLSTM. Specifically, from a timeline perspective, ASLSTM concatenates several BLSTMs to predict the concentration of PM at the following next several hours during which the predicted outputs of BLSTM at this time t was selected and included as the inputs of the next BLSTM at the next time t + 1, and the oldest input used as BLSTM at the time t was removed. The result demonstrated that BLSTM were trained by the dataset collected from 2008 to 2010 at Dali measurement station because there is a relatively large amount of data on high PM concentration in this dataset. Besides, a comparison of the performance of the ASLSTM with that of the LSTM was made to validate this proposed ASLSTM, especially for the range of higher PM concentration that people concerned. More importantly, the feasibility of this proposed application strategy and the necessity of optimizing the input parameters of LSTM were validated. In summary, this ASLSTM could accurately predict the short-term PM in Taichung city.
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http://dx.doi.org/10.1016/j.scitotenv.2023.167892 | DOI Listing |
Viruses
December 2024
Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd., Beijing 100176, China.
Human respiratory syncytial virus (RSV) remains a significant global health threat, particularly for vulnerable populations. Despite extensive research, effective antiviral therapies are still limited. To address this urgent need, we present AVP-GPT2, a deep-learning model that significantly outperforms its predecessor, AVP-GPT, in designing and screening antiviral peptides.
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December 2024
Life Sciences, Health, and Engineering Department, The Roux Institute, Northeastern University, Portland, ME 04101, USA.
JC polyomavirus (JCPyV) establishes a persistent, asymptomatic kidney infection in most of the population. However, JCPyV can reactivate in immunocompromised individuals and cause progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease with no approved treatment. Mutations in the hypervariable non-coding control region (NCCR) of the JCPyV genome have been linked to disease outcomes and neuropathogenesis, yet few metanalyses document these associations.
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January 2025
Institute for Polymers Composites and Biomaterials, Italian National Research Council, Piazzale Enrico Fermi, 80055 Portici, NA, Italy.
This work introduces an experimental approach focused on investigating fatigue-driven debonding in a composite structure designed to simulate the complexity of a typical aeronautical panel. The debonding is placed between the skin and the stringer, and the structure has been tested under fatigue compression conditions. Using lock-in thermography, the damage evolution during fatigue cycles has been detailed monitored.
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January 2025
Department of Mechanical Engineering, Hanyang University, 222 Wangsimri-ro, Seongdong-gu, Seoul 04763, Republic of Korea.
This study presents a methodology for characterizing the constituent properties of composite materials by back-calculating from the laminate behavior under fatigue loading. Composite materials consist of fiber reinforcements and a polymer matrix, with the fatigue performance of the laminate governed by the interaction between these constituents. Due to the challenges in directly measuring the properties of individual fibers and the polymer matrix, a reverse-engineering approach was employed.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
College of Pharmacy, Dankook University, 119, Dandae-ro, Dongnam-gu, Cheonan-si 31116, Republic of Korea.
: This study aimed to establish a predictive model for critical quality attributes (CQAs) related to tablet integrity, including tablet breaking force (TBF), friability, and capping occurrence, using machine learning-based models and nondestructive experimental data. : The machine learning-based models were trained on data to predict the CQAs of metformin HCl (MF)-containing tablets using a commercial-scale wet granulation process, and five models were each compared for regression and classification. We identified eight input variables associated with the process and material parameters that control the tableting outcome using feature importance analysis.
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