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Operation Polypharmacy: a pharmacist-led ambulatory care clinic design and evaluation for older patients.
Sci Rep
December 2024
Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
The unintended consequences of polypharmacy pose significant risks to older adults. The complexities of managing numerous medications from multiple prescribers demand a comprehensive approach to mitigate harms. Pharmacist-led clinics have been shown to improve outcomes in patients with diabetes and hypertension.
View Article and Find Full Text PDFIntegration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema.
J Biophotonics
December 2024
Medical Faculty, Ophthalmology Department, University of Health Sciences, Istanbul, Türkiye.
The primary ocular effect of diabetes is diabetic retinopathy (DR), which is associated with diabetic microangiopathy. Diabetic macular edema (DME) can cause vision loss for people with DR. For this reason, deciding on the appropriate treatment and follow-up has a critical role in terms of curing the disease.
View Article and Find Full Text PDFBeneficial Effects of Tilapia Fish Skin on Excisional Skin Wound Healing in a Type I Diabetic Rat Model.
J Biomed Mater Res B Appl Biomater
January 2025
Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
IntroductionProlonged hyperglycemia in diabetic patients often impairs wound healing, leading to chronic infections and complications. This study aimed to evaluate the potential of fresh Tilapia fish skin as a treatment to enhance wound healing in diabetic rats. MethodsThirty-nine healthy adult albino rats, weighing between 150 and 200 g, were divided into three groups: non-diabetic rats with untreated wounds [C-], diabetic rats with untreated wounds [C+], and diabetic rats treated with fresh Tilapia skin [TT].
View Article and Find Full Text PDFNon-antibiotic approaches to mitigating wound infections: Potential for SSRIs and adrenergic antagonists as emerging therapeutics.
Wound Repair Regen
December 2024
Department of Dermatology, University of California Davis School of Medicine, Sacramento, California, USA.
Bacterial biofilms represent a formidable challenge in the treatment of chronic wounds, largely because of their resistance to conventional antibiotics. The emergence of multidrug-resistant (MDR) bacterial strains exacerbates this issue, necessitating a shift towards exploring alternative therapeutic approaches. In response to this urgent need, there has been a surge in research efforts aimed at identifying effective non-antibiotic treatments.
View Article and Find Full Text PDFEfficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy.
J Pain Res
December 2024
Department of Pain Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, People's Republic of China.
Background: The best tool for the management of pain associated with distal symmetric peripheral neuropathy (DSPN) is a matter of debate. Therefore, the study aimed to explore whether ultrasound-guided pulsed radiofrequency (PRF) therapy of the stellate ganglion (SG) in type 2 diabetes mellitus (T2DM) patients with painful DSPN could decrease pain severity and the need for analgesics.
Methods: Fifty-six T2DM patients with refractory painful DSPN were enrolled in this study, who then received bilateral ultrasound-guided PRF therapy of SG.
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