Terahertz (THz) waves are electromagnetic waves with frequency in the range from 0.1 to 10 THz. THz waves have great potential in the biomedical field, especially in cancer diagnosis, because they exhibit low ionization energy and can be used to discern most biomolecules based on their spectral fingerprints. In this paper, we review the recent progress in two applications of THz waves in cancer diagnosis: imaging and spectroscopy. THz imaging is expected to help researchers and doctors attain a direct intuitive understanding of a cancerous area. THz spectroscopy is an efficient tool for component analysis of tissue samples to identify cancer biomarkers. Additionally, the advantages and disadvantages of the developed technologies for cancer diagnosis are discussed. Furthermore, auxiliary techniques that have been used to enhance the spectral signal-to-noise ratio (SNR) are also reviewed.
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http://dx.doi.org/10.34133/2020/2547609 | DOI Listing |
Bioengineering (Basel)
January 2025
Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Terahertz (THz) waves reside in the electromagnetic spectrum between the microwave and infrared bands. In recent decades, THz technology has demonstrated its potential for biomedical applications. With the highly unique characteristics of THz waves, such as the high sensitivity to water and optimal spatial resolution coupled with the characteristics of the human cornea, such as its high water content, THz technology has been explored as a potential modality to assess corneas and corneal diseases.
View Article and Find Full Text PDFResearch (Wash D C)
January 2025
Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210023, China.
This paper reviews recent developments and key advances in terahertz (THz) science, technology, and applications, focusing on 3 core areas: astronomy, telecommunications, and biophysics. In THz astronomy, it highlights major discoveries and ongoing projects, emphasizing the role of advanced superconducting technologies, including superconductor-insulator-superconductor (SIS) mixers, hot electron boundedness spectroscopy (HEB), transition-edge sensors (TESs), and kinetic inductance detectors (KIDs), while exploring prospects in the field. For THz telecommunication, it discusses progress in solid-state sources, new communication technologies operating within the THz band, and diverse modulation methods that enhance transmission capabilities.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Inner Mongolia Grassland Station, Huhhot, Inner Mongolia 010020, China. Electronic address:
Owing to the complicated geographical locations and climates, cultivation and selection of forage seeds are challenging. For the first time, we qualitatively distinguished the drought and cold resistance of forage seeds with the time domain and refractive index spectra using terahertz (THz) time-domain spectroscopy. A multilayer structure propagation (MSP) model was developed based on the effective medium and light transport theory to reveal the underlying biological mechanisms of drought and cold resistance of forage seeds.
View Article and Find Full Text PDFSci Rep
January 2025
Terahertz Research Section, Electronics and Telecommunications Research Institute, Deajeon, 34129, Republic of Korea.
The complex dynamics of terahertz (THz) wave scattering by subwavelength-scale structures remain largely unexplored. This article examines the spectral scattering characteristics of subwavelength-sized spherical particles probed by tightly focused THz waves through numerical simulations and experimental techniques. The simulations reveal that the scattering intensity for lower Mie resonance modes (magnetic dipole and electric dipole modes) remains largely unaffected when THz waves are focused down to 0.
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
State Key Laboratory of Millimeter-Waves, School of Information Science and Engineering, Southeast University, Nanjing 210096, China.
This paper presents a D-band dual linear-polarized wideband high-gain reflectarray (RA) antenna using low-temperature co-fired-ceramic (LTCC) technology. The proposed element comprises a dual-polarized magnetoelectric (ME) dipole and a multilayer slot-coupling substrate-integrated waveguide (SIW) phase-delay structure, which are organized in accordance with the receiving/reradiating (R/R) principle. The coverage of phase shifts for both orthogonal polarizations is set to be greater than 360 degrees by varying the length of the phase-delay structure.
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