AI Article Synopsis
- * In a study involving 12,653 slaughtered sheep in Jeddah, Saudi Arabia, researchers amplified and sequenced the ITS-1 region of Fasciola adult worms, discovering 12 different DNA variants with a high similarity to sequences from other countries.
- * The research concluded that the only Fasciola species found in the sheep studied was specific to Jeddah, indicating the need for further research across Saudi Arabia for better disease management.
Article Abstract
Introduction: World Health Organization (WHO) considers Fascioliasis as a neglected tropical disease that requires global efforts for disease control. Data from the genetic characterization of population shed light on the spread of infections among animals which could help in the development of effective parasite control. The aim of the present work was to genetically characterize Fasciola adult worms isolated from sheep in Saudi Arabia by sequence analysis of ITS-1 region.
Methods: A total of 12,653 slaughtered sheep in Jeddah city, Saudi Arabia were examined for the presence of spp. adult worms. The ITS-1 region of all parasites was amplified and sequenced.
Results: Overall, 12 variants DNA sequences were obtained. The variance of isolates ranged from 0.00771 to 0.34405. BLAST search showed that all obtained sequences and had >99.3% similarity with isolates from Spain and USA (from different hosts other than sheep). Phylogenetic analysis showed that isolates were closely related to isolates from different countries.
Discussion: The current study showed that was the only spp. isolated from sheep in Jeddah. Further studies from different localities in Saudi Arabia are needed to help in the development of disease control.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578168 | PMC |
| http://dx.doi.org/10.2147/IDR.S421206 | DOI Listing |
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