AI Article Synopsis
- High-precision bioengineering and synthetic biology require careful regulation of gene expression at both transcriptional and posttranscriptional levels, influenced by promoters and terminators.
- Promoters control when, where, and how much a gene is expressed, while terminators are crucial for stopping transcription and impact mRNA processing and stability.
- The article reviews different types of plant promoters and terminators, discussing their roles and strategies for optimizing gene expression in bioengineering.
Article Abstract
High-precision bioengineering and synthetic biology require fine-tuning gene expression at both transcriptional and posttranscriptional levels. Gene transcription is tightly regulated by promoters and terminators. Promoters determine the timing, tissues and cells, and levels of the expression of genes. Terminators mediate transcription termination of genes and affect mRNA levels posttranscriptionally, e.g., the 3'-end processing, stability, translation efficiency, and nuclear to cytoplasmic export of mRNAs. The promoter and terminator combination affects gene expression. In the present article, we review the function and features of plant core promoters, proximal and distal promoters, and terminators, and their effects on and benchmarking strategies for regulating gene expression.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328392 | PMC |
| http://dx.doi.org/10.34133/bdr.0013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!