Background: Open abdomen is an alternative for the management of trauma patient, and negative pressure therapy of the wound using VAC device is a genuine sort of treatment. Although the device poses technical advantages, risks are present and a critical complication is the enteroatmospheric fistula formation (EAF).
Objective: To analize the role of negative pressure therapy length and VAC device number of changes on the EAF formation in trauma patients udergoing open abdomen.
Method: Cut-off points were calculated using receiver operational characteristics curve. Values were compared with Student's t or Mann-Withney U tests, considering statistically significant p < 0.05.
Results: EAF were present in 39 cases (5.9%). A significant difference in the presence of EAF was present in patients with negative pressure therapy of the wound length ≥ 11.2 days (46.9 vs. 1.3%; relative risk [RR]: 3.67; 95% confidence interval [95% IC]: 2.4-6.68; p = 0.017) and when ≥ 2.6 VAC device changes were performed (34.6 vs. 0.5%; RR: 6.92; 95% IC: 1.1-4.3; p < 0.001).
Conclusions: At our institution, the practice of >3 VAC device changes and length of therapy > 11 days should be carefully considered leading to reduce the risk of EAF formation.
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