Relevance of a bone and joint registry for fracture-related infections.

J Orthop

Department of Arthroplasty, Northumbria Healthcare NHS Foundation Trust, UK.

Published: November 2023

The UK Bone and Joint Infection Registry (BAJIR) is a national project established in 2018 with the aim of collecting information about demographics, co-morbidities, pathogens, treatment strategies and outcomes on all patients who are diagnosed with, and treated for, a bone or joint infection in the UK with the objective of providing an understanding of the burden of disease. In time these data will be used to inform best practice, direct research and provide information for commissioners of healthcare. In this fracture-related infection special edition article, we discuss the registry's development, relevance and how we see it directing our practice in the future. Equally, we have highlighted some potential limitations and lessons learned.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570625PMC
http://dx.doi.org/10.1016/j.jor.2023.09.004DOI Listing

Publication Analysis

Top Keywords

bone joint
12
joint infection
8
relevance bone
4
joint registry
4
registry fracture-related
4
fracture-related infections
4
infections bone
4
infection registry
4
registry bajir
4
bajir national
4

Similar Publications

A large-scale multi-omics polygenic risk score analysis identified candidate risk locus associated with rheumatoid arthritis.

Joint Bone Spine

December 2024

Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, 710061 Xi'an, China. Electronic address:

Objective: This study aimed to investigate the associations of multi-omics polygenic risk score (PRS) and rheumatoid arthritis (RA) to identify potential genes/proteins and biological pathways.

Methods: Based on multi-omics data from 48,813 participants in the INTERVAL cohort, we calculated multi-omics PRS for 13,646 mRNAs (RNASeq), 308 proteins (Olink), 2,380 proteins (SomaScan), 726 metabolites (Metabolon), and 141 metabolites (Nightingale). Using the generalized linear model, we first evaluated the associations between multi-omics PRS and RA in 58,813 UK Biobank participants.

View Article and Find Full Text PDF

Predictors of return to work after multidisciplinary rehabilitation program for patients with chronic low back pain.

Joint Bone Spine

December 2024

Rheumatology department, Pitié-Salpêtrière hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), 47-83 boulevard de l'hôpital, 75013 Paris, France; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Pharmacologie et évaluation des soins, AP-HP, Hôpital Pitié Salpêtrière, Centre de la douleur, F75013, Paris, France.

Introduction: Patients with chronic low back pain face functional, psychological, social and professional difficulties. Multidisciplinary Rehabilitation Programs (MRP) can be an effective treatment to help these patients to improve their condition and return to work.

Objective: To determine baseline predictors for return to work after an MRP for patients with chronic low back pain struggling to maintain their job.

View Article and Find Full Text PDF

Background: Total hip arthroplasty is the preferred treatment for advanced hip osteoarthritis, yet complications like hip dislocation (0.2 %-10 %) persist due to factors such as implant design, positioning, surgical technique, and patient-specific conditions. Impingement between prosthetic components or the acetabulum and proximal femur is a primary cause of instability.

View Article and Find Full Text PDF

Purpose Of Review: The canonical pathogenesis of spondyloarthritis (SpA) involves inflammation driven by HLA-B27, type 3 immunity, and gut microbial dysregulation. This review based on information presented at the SPARTAN meeting highlights studies on the pathogenesis of SpA from the past year, focusing on emerging mechanisms such as the roles of microbe-derived metabolites, microRNAs (miRNAs) and cytokines in plasma exosomes, specific T cell subsets, and neutrophils.

Recent Findings: The induction of arthritis in a preclinical model through microbiota-driven alterations in tryptophan catabolism provides new insights as to how intestinal dysbiosis may activate disease via the gut-joint axis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!