Applying the digital data and the bioinformatics tools in SARS-CoV-2 research.

Comput Struct Biotechnol J

School of Life Sciences, Chongqing University, Chongqing, China.

Published: October 2023

Bioinformatics has been playing a crucial role in the scientific progress to fight against the pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The advances in novel algorithms, mega data technology, artificial intelligence and deep learning assisted the development of novel bioinformatics tools to analyze daily increasing SARS-CoV-2 data in the past years. These tools were applied in genomic analyses, evolutionary tracking, epidemiological analyses, protein structure interpretation, studies in virus-host interaction and clinical performance. To promote the analysis in the future, we conducted a review which summarized the databases, web services and software applied in SARS-CoV-2 research. Those digital resources applied in SARS-CoV-2 research may also potentially contribute to the research in other coronavirus and non-coronavirus viruses.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568291PMC
http://dx.doi.org/10.1016/j.csbj.2023.09.044DOI Listing

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