Objectives: The current recommended treatment for severe fetal anemia is transfusion (IUT). During this procedure, the evaluation of the necessary volume of transfused blood is based on regular measurement of fetal hemoglobin (FHb) concentration. The gold standard measurement is performed in the biology laboratory. A rapid medical test such as HemoCue is an effective way to predict FHb concentration. It would reduce the time to obtain results and therefore the procedure duration. To evaluate the accuracy of HemoCue to measure FHb during IUT, we compared Hb levels obtained by HemoCue and by our biology laboratory.
Methods: This retrospective study involved all pregnant women who had undergone an IUT in the university hospital of Clermont-Ferrand, France, during the period from 1 January 2010 to 6 June 2021. The FHb level was evaluated by two methods, a rapid medical test, HemoCue, and a standard method in the biology laboratory.
Results: We obtained 244 pairs of results from HemoCue and our laboratory, of 90 IUT procedures. The correlation between the two sets of results was excellent, with Lin's concordance correlation coefficient of 0.979. However, we established that the measurements were not significantly modified by IUT number, puncture time, cause of fetal anemia, estimated fetal weight, gestational age, and delay between two IUT or middle cerebral artery peak systolic velocity values.
Conclusion: Our results allowed to extend the relevance of FHb measurements by HemoCue during IUT.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14767058.2023.2266092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Consumption of ultra-processed foods is associated with dietary iron availability, anemia, and excess weight in socially vulnerable children.
Clin Nutr ESPEN
December 2024
Programa de Pós-Graduação em Nutrição, Escola Paulista de Medicina, Universidade Federal de São Paulo. Electronic address:
Background & Aims: Eating habits during childhood have undergone significant changes, with a notable increase in the consumption of ultra-processed foods (UPF). This situation deserves attention, given the close relationship between UPF and adverse health outcomes. This is due to the nutritional composition of UPF, which has high levels of health-critical nutrients such as sugar, fat, and sodium, thus compromising the overall quality of the diet.
View Article and Find Full Text PDFEnhancing Anemia Detection With Non-invasive Anemia Detection With AI (NiADA): Insights From Clinical Validations and Physician Observations.
Cureus
December 2024
Artificial Intelligence, Monere AI, Lehi, USA.
Background Anemia, a critical public health issue, affects nearly two billion people globally. Frequent monitoring of blood hemoglobin levels is essential for managing its burden. While point-of-care testing (POCT) devices facilitate hemoglobin testing in resource-limited settings, most are invasive and have inherent limitations.
View Article and Find Full Text PDFEvaluation of the Performance of Portable Hemoglobinometers at Measuring Hemoglobin and Detecting Anemia in a Periurban Pediatric Population in Lima, Peru.
Am J Trop Med Hyg
December 2024
Laboratorio de Bioinformática, Biología Molecular y Desarrollos Tecnológicos, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias e ingeniería, Universidad Peruana Cayetano Heredia.
As many as one in three people worldwide have anemia, with young children at increased risk of both disease and complications. In settings without clinical laboratories, portable hemoglobinometers serve important roles in diagnosing anemia and estimating prevalence. Here, we assess the validity of two such point-of-care devices-the HemoCue Hb201 and the HemoCue Hb301-relative to the international reference standard, the cyanmethemoglobin method.
View Article and Find Full Text PDF[Use of HemoCue® or portable hemoglobinometer: results of the national surveys carried out by the SFBC POCT working group].
Ann Biol Clin (Paris)
November 2024
Biochimie et Cellule de Biologie Délocalisée, CHU de Bordeaux, Place Amélie Raba Léon, et UNR5536 CNRS-Université de Bordeaux, 33000 Bordeaux, France.
Hemoglobin (Hb) measurement is a fundamental biological test, especially in emergency situations where rapid medical decisions are required. Portable hemoglobinometers, such as HemoCue®, provide a delocalized solution for capillary whole blood. The SFBC's POCT News and Issues working group designed and conducted two national surveys to assess the use and management of these devices, both on the clinical and biological side, with 306 and 160 responses respectively.
View Article and Find Full Text PDFComparison of haemoglobin concentration measurements using HemoCue-301 and Sysmex XN-Series 1500: A survey among anaemic Gambian infants aged 6-12 months.
PLoS One
November 2024
Medical Research Council (MRC) Unit The Gambia at London School of Hygiene & Tropical Medicine (LSHTM), Fajara, The Gambia.
Article Synopsis
- In low-income countries, photometers like HemoCue-301 are used to screen and manage anaemia and assess iron status for public health interventions.
- This study evaluated the accuracy of HemoCue-301 in determining haemoglobin levels in anaemic children aged 6-12 months in rural Africa, using a more precise reference method, Sysmex XN-1500.
- Results showed significant bias in HemoCue-301 measurements for children with haemoglobin below 8.0g/dL, indicating it may not reliably measure low haemoglobin levels in this population.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!