Association between air pollution and sudden sensorineural hearing loss (SSHL): A systematic review and meta-analysis.

Environ Res

Department of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 87-95123, Catania, Italy. Electronic address:

Published: December 2023

AI Article Synopsis

  • Recent studies suggest that air pollution negatively affects hearing and can lead to ear diseases, particularly Sudden Sensorineural Hearing Loss (SSHL).
  • The study reviewed 1146 initial studies, narrowing down to 8 relevant studies, and assessed their quality and risk of bias before conducting a meta-analysis.
  • Results indicated higher levels of specific air pollutants in patients with SSHL compared to controls, with particulate matter (PM) showing a significant relationship, but overall more research is needed to clarify these findings and understand the underlying mechanisms.

Article Abstract

Recent studies have indicated that air pollution (AP) has harmful effects on hearing and ear diseases such as Sudden Sensorineural Hearing Loss (SSHL). The purpose of this study was to evaluate the impact of exposure to AP on SSHL incidence. Valid electronic databases were searched to retrieve studies published until December 1, 2022, using appropriate keywords. The result of the search was 1146 studies, and after screening according to the defined criteria, in total 8 studies were obtained. The risk of bias (ROB) in the studies and their quality were assessed. Finally, the meta-analysis with a significance level of 5% was performed. The findings revealed that the mean level of SO, CO, NO, and PM in the patient group was more than that of the control group, and p-values were 0.879, 0.144, 0.077, and 0.138, respectively. There was an indirect relation between air pollutants and SSHL, and PM showed a significant effect (p < 0.05). Given the limited research and the use of different statistical methods, more research is suggested to confirm this association and to determine the mechanisms by which AP exposure may cause SSHL.

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http://dx.doi.org/10.1016/j.envres.2023.117392DOI Listing

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