Multi-omics analysis of metastatic pancreatic cancer reveals an immunosuppressive landscape.

Med

Henry Ford Pancreatic Cancer Center, Department of Surgery, Henry Ford Hospital, Detroit, MI 48202, USA; Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48202, USA. Electronic address:

Published: October 2023

Immune cell populations play key functional roles in tumor growth and metastasis, and multi-omic approaches can map cellular interactions to identify targets for highly immunosuppressive and treatment resistant cancers. In this issue of Med, Zhang et al. investigate the immune cell landscape of advanced pancreatic cancer to understand the mechanisms underlying liver metastasis.

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http://dx.doi.org/10.1016/j.medj.2023.09.005DOI Listing

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