The antioxidant activity (AA) of hop extracts obtained from different hop genotypes ( = 14) was studied. For comparison, the purified β-acids-rich fraction and α-acids-with-β-acids-rich fraction were also used to test the antioxidative potential. The AA of purified hydroacetonic hop extracts was investigated using the Ferric Reducing Ability of Plasma (FRAP), Oxygen Radical Absorption Capacity (ORAC) and Intracellular Antioxidant (IA) methods. The FRAP values in different hop genotypes ranged between 63.5 and 101.6 μmol Trolox equivalent (TE)/g dry weight (DW), the ORAC values ranged between 1069 and 1910 μmol TE/g DW and IA potential values ranged between 52.7 and 118.0 mmol TE/g DW. Significant differences in AA between hop genotypes were observed with all three methods. AAs were determined using three different methods, which did not highly correlate with each other. We also did not find significant correlations between AA and different chemical components, which applies both to AA determined using individual methods as well as the total AA. Based on this fact, we assume that the synergistic or antagonistic effects between hop compounds have a more pronounced effect on AA than the presence and quantity of individual hop compounds.
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http://dx.doi.org/10.3390/plants12193436 | DOI Listing |
Brief Bioinform
September 2024
School of Automation Science and Engineering, Xi'an Jiaotong University, Xi'an, Shannxi 710049, China.
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Thuy Phuong Pig Research Center, Ha Noi City, Vietnam.
Piglet lethality is one of the major concerns in pig breeding programs. Deletion of a 212-kb region within the Bardet-Biedl syndrome 9 () gene has been linked to a reduction in the number of piglets born alive per litter. The mutant gene carrier-by-carrier mating scheme could result in mummification of piglets carrying 2 copies of the mutant allele, which ultimately affects the reproductive performance of the sow.
View Article and Find Full Text PDFNat Genet
July 2024
Department of Neurology, UMass Chan Medical School, Worcester, MA, USA.
Despite substantial progress, causal variants are identified only for a minority of familial Parkinson's disease (PD) cases, leaving high-risk pathogenic variants unidentified. To identify such variants, we uniformly processed exome sequencing data of 2,184 index familial PD cases and 69,775 controls. Exome-wide analyses converged on RAB32 as a novel PD gene identifying c.
View Article and Find Full Text PDFIEEE/ACM Trans Comput Biol Bioinform
October 2024
CircRNA has been shown to be involved in the occurrence of many diseases. Several computational frameworks have been proposed to identify circRNA-disease associations. Despite the existing computational methods have obtained considerable successes, these methods still require to be improved as their performance may degrade due to the sparsity of the data and the problem of memory overflow.
View Article and Find Full Text PDFPlants (Basel)
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Department of Biological Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
The increased cultivation of high THC-containing L. (cannabis), particularly in greenhouses, has resulted in a greater incidence of diseases and molds that can negatively affect the growth and quality of the crop. Among them, the most important diseases are root rots ( and spp.
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