AI Article Synopsis

  • Oral submucous fibrosis (OSF) is a progressive oral condition linked to a risk of cancer, making it important for early diagnosis.
  • The review focuses on exploring various biomarkers that could help in the early detection of OSF, highlighting the methods used to collect and analyze these biomarkers.
  • Four specific biomarkers are discussed as promising candidates for improving diagnostic tools for identifying early stages of OSF.

Article Abstract

Oral submucous fibrosis (OSF) stands as a progressive oral ailment, designated as a potentially malignant disorder. OSF has gained widespread recognition as a significant precursor to malignant transformation. In the pursuit of dependable, straightforward, and non-invasive diagnostic measures for the early detection of oral malignant progression, research has delved into potential diagnostic biomarkers of OSF. This comprehensive review delves into current investigations that explore the correlation between various biomarkers and OSF. The molecular biomarkers of OSF are categorized based on cytology and sampling methods. Moreover, this review encompasses pertinent studies detailing how these biomarkers are acquired and processed. Within this scope, we scrutinize four potential biomarkers that hold the promise of facilitating the development of diagnostic tools for detecting early-stage OSF.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571555PMC
http://dx.doi.org/10.3390/cancers15194812DOI Listing

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