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http://dx.doi.org/10.1016/j.jid.2023.09.273 | DOI Listing |
JAMA Cardiol
March 2025
Department of Cardiovascular Medicine and Section on Geriatrics and Gerontology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Importance: Excess body fat plays a pivotal role in the pathogenesis of heart failure with preserved ejection fraction (HFpEF). HU6 is a novel, controlled metabolic accelerator that enhances mitochondrial uncoupling resulting in increased metabolism and fat-specific weight loss.
Objective: To assess efficacy and safety of HU6 in reducing body weight, improving peak volume of oxygen consumption (VO2) and body composition among patients with obesity-related HFpEF.
World J Emerg Surg
March 2025
Department of Trauma Surgery and Orthopedics, Goethe University Frankfurt, University Hospital, 60590, Frankfurt, Germany.
Background: Heart injuries following polytrauma (PT) are identified as a predictor of poor outcome. The diagnostic algorithm of cardiac damage after trauma consists of the systemic measurement of cardiac damage markers, a 3-channel ECG and if there are any suspicious findings, the conduction of a transthoracic echocardiography (TTE). The aim of this study was to implement a systematic analysis of cardiac function using TTE in PT-patients.
View Article and Find Full Text PDFSyst Rev
March 2025
Department of Cardiology, Guang'Anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Background: Chinese classical prescriptions (CCPs) are commonly utilized in China as an adjuvant treatment for dilated cardiomyopathy (DCM). Nevertheless, there was insufficient systematic evidence data to show the advantages of CCPs plus current conventional therapy (CT) against DCM. This network meta-analysis (NMA) sought to evaluate and prioritize the six different CCP types' respective efficacies for DCM.
View Article and Find Full Text PDFDermatitis
March 2025
Dr. Phillip Frost Dept of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller School of Medicine, Coral Gables, FL, USA.
Itch is a debilitating symptom that affects ∼40% of the population and significantly impacts patients' quality of life. The management of chronic itch remains a significant challenge due to the limited availability of reliable biomarkers for assessing its severity. This review aims to investigate the key neuroimmune-related biomarkers involved in the pathophysiology of itch and itch-dependent diseases.
View Article and Find Full Text PDFBackground: We aimed to investigate the correlations of prealbumin (PA), procalcitonin (PCT) and brain natriuretic peptide (BNP) with acute respiratory infection (ARI) in children.
Methods: A total of 120 children with ARI admitted from June 2021 through June 2023 were selected (an infection group) and divided into a bacteria group (n = 50) and a virus group (n = 70) according to the results of bacterial culture and serum test. Another 90 healthy children who underwent physical examination in the same period were selected as a control group.
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