Invited for the cover of this issue is the group of Masaki Yoshida and Masako Kato at Hokkaido University/Kwansei Gakuin University. The image depicts the changes in the assembly of Pt complexes with humidity on layered double hydroxide (LDH) nanoparticles, resulting in a drastic emission color change from green to orange. Read the full text of the article at 10.1002/chem.202301993.
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A coarse-grained model of clay colloidal aggregation and consolidation with explicit representation of the electrical double layer.
J Colloid Interface Sci
December 2024
Department of Civil and Environmental Engineering, Princeton University, Princeton, NJ 08544, USA; High Meadows Environmental Institute, Princeton University, Princeton, NJ 08544, USA. Electronic address:
Knowledge Gap: The aggregation of clay minerals in liquid water exemplifies colloidal self-assembly in nature. These negatively charged aluminosilicate platelets interact through multiple mechanisms with different sensitivities to particle shape, surface charge, aqueous chemistry, and interparticle distance and exhibit complex aggregation structures. Experiments have difficulty resolving the associated colloidal assemblages at the scale of individual particles.
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J Prosthodont
January 2025
Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Lagoa Nova, Natal, Brazil.
Purpose: To assess the impact of staining and multiple firings on the mechanical, optical, and surface characteristics of zirconia-containing lithium silicate ceramics (ZLS).
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Machine learning assisted plasmonic metascreen for enhanced broadband absorption in ultra-thin silicon films.
Light Sci Appl
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Division of Computer, Electrical and Mathematical Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.
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View Article and Find Full Text PDFThe construction of a double-layer colon-targeted delivery system based on zein-shellac complex and gelatin-isomaltooligosaccharide Maillard product: In vitro and in vivo evaluation.
Food Res Int
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College of Life Sciences, Northeast Forestry University, Harbin 150040, PR China; Key Laboratory of Forest Food Resources Utilization of Heilongjiang Province, Harbin 150040, PR China. Electronic address:
In this study, we developed a double-layer colon-targeted microcapsule. It used the Maillard product of gelatin-isomaltooligosaccharide (GI180) and zein-shellac complex (ZS) as bio-based materials, plant extracts (MPL) and Lactobacillus plantarum JJBYG12 (JJBYG12) were co-encapsulated, endowing them with strong resistance to harsh environments and precise intestinal adhesion and targeting ability. The research results indicated that ZS11 exhibits hydrogen bonding and electrostatic interactions.
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Biomaterials
January 2025
Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen, 518107, China; School of Medicine, Hangzhou City University, Hangzhou, 310015, China; Guoke Ningbo Life Science and Health Industry Research Institute, Ningbo, 315040, China. Electronic address:
T cell therapy for solid tumors faces significant challenges due to the immune off-target attack caused by the loss of tumor surface antigens and inactivation in acidic tumor microenvironment (TME). Herein, we developed a bifunctional immunomodulator (MO@NAL) by loading ovalbumin (OVA; model antigen) mRNA (mOVA) onto lysozyme-coated layered double hydroxide nano-aluminum adjuvant (NA). The NA's inherent alkalinity effectively neutralizes the excess acid within the TME and suppresses regulatory T cells, creating a favorable microenvironment to enhance cytotoxic T cell infiltration and activation in tumors.
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