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Inclusion of Labor Migrants as a Potential Key Population for HIV: A Nationwide Study from Tajikistan.
Trop Med Infect Dis
December 2024
Department of Health Science, College of Health and Human Services, California State University Long Beach, Long Beach, CA 90840, USA.
Key populations are particularly vulnerable to human immunodeficiency virus (HIV) infection. Nearly half of Tajikistan's gross domestic product (GDP) originates from labor migrant transfers. While not officially designated as a key population, over 300,000 migrants return to Tajikistan every year at increased risk for HIV due to absence or interruption of treatment, change in risky behaviors, and other factors.
View Article and Find Full Text PDFAcetylation-Mediated Post-Translational Modification of Pyruvate Dehydrogenase Plays a Critical Role in the Regulation of the Cellular Acetylome During Metabolic Stress.
Metabolites
December 2024
Division of Metabolic and Cardiovascular Sciences, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Cardiac diseases remain one of the leading causes of death globally, often linked to ischemic conditions that can affect cellular homeostasis and metabolism, which can lead to the development of cardiovascular dysfunction. Considering the effect of ischemic cardiomyopathy on the global population, it is vital to understand the impact of ischemia on cardiac cells and how ischemic conditions change different cellular functions through post-translational modification of cellular proteins. : To understand the cellular function and fine-tuning during stress, we established an ischemia model using neonatal rat ventricular cardiomyocytes.
View Article and Find Full Text PDFIntegrated Transcriptomic and Metabolomic Analysis Reveals Possible Molecular Mechanisms of Leaf Growth and Development in var. .
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November 2024
Institute of Plant Conservation, Hunan Botanical Garden, Changsha 411006, China.
var. is an ancient relic plant unique to China. However, the typical shade-loving plant is largely exposed to the sun, which poses a major challenge to its conservation.
View Article and Find Full Text PDFUnveiling Metabolic Crosstalk: -Mediated Defense Priming in Pine Needles Against Pathogen Infection.
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November 2024
Key Laboratory of National Forestry and Grassland Administration on Control of Artificial Forest Diseases and Pests in South China, Central South University of Forestry and Technology, Changsha 410004, China.
Plant growth-promoting rhizobacteria (PGPR), particularly spp., are pivotal in enhancing plant defense mechanisms against pathogens. This study aims to investigate the metabolic reprogramming of pine needles induced by csuftcsp75 in response to the pathogen P9, evaluating its potential as a sustainable biocontrol agent.
View Article and Find Full Text PDFGlobal Analysis of microRNA-like RNAs Reveals Differential Regulation of Pathogenicity and Development in Causing Apple Replant Disease.
J Fungi (Basel)
December 2024
State Key Laboratory of North China Crop Improvement and Regulation, College of Plant Protection, Hebei Agricultural University, Baoding 071000, China.
This study investigated the expression profiles of microRNA-like RNAs (milRNAs) in (), a key pathogen causing Apple replant disease (ARD), across spore to mycelium formation stages. Using small RNA sequencing (sRNA-seq) and bioinformatics, we identified and analyzed milRNAs, revealing their targeting of 2364 mRNAs involved in 20 functional categories, including metabolic and cellular processes, based on gene ontology (GO) analysis. An analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG) showed that these mRNAs are related to carbohydrate and amino acid metabolism pathways.
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