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Association Between MScanFit Motor Unit Number Estimation and Clinical Function and Response to Immunoglobulin Therapy in Chronic Inflammatory Demyelinating Polyneuropathy.
J Peripher Nerv Syst
March 2025
Neurology Research Unit, Odense University Hospital, Odense, Denmark, University of Southern Denmark, Odense, Denmark.
Background And Aims: Loss of motor units in chronic inflammatory demyelinating polyneuropathy is difficult to assess by conventional nerve conduction due to collateral innervation. We aimed to assess the association between a motor unit number estimate (MUNE) derived from the compound muscle action potential (CMAP) scan using MScanFit and hand function and the clinical response to intravenous immunoglobulin (IVIG).
Methods: Forty-nine CIDP patients and 52 control subjects were included.
Direct and indirect genetic effects on early neurodevelopmental traits.
J Child Psychol Psychiatry
January 2025
Research Department, Lovisenberg Diaconal Hospital, Oslo, Norway.
Background: Neurodevelopmental conditions are highly heritable. Recent studies have shown that genomic heritability estimates can be confounded by genetic effects mediated via the environment (indirect genetic effects). However, the relative importance of direct versus indirect genetic effects on early variability in traits related to neurodevelopmental conditions is unknown.
View Article and Find Full Text PDF'Muscular wisdom' revisited: Decaying rates of stimulation mitigate torque loss.
Exp Physiol
January 2025
School of Kinesiology, Faculty of Health Sciences, The University of Western Ontario, London, Ontario, Canada.
During a sustained high-intensity isometric maximal voluntary contraction (MVC), declining motor unit firing rates (MUFRs) accompany torque loss. This decline (∼50% over 60 s) helps to maintain torque by preserving peripheral electrical propagation and matching the slowing contractile properties with torque loss (i.e.
View Article and Find Full Text PDFThe epidemiological characteristics of major trauma in Pietersburg and Mankweng hospitals, Limpopo province.
S Afr J Surg
December 2024
Trauma and Burns Unit, Inkosi Albert Luthuli Central Hospital, South Africa.
Background: Data on trauma burden and outcome varies amongst the nine South African Provinces. In Limpopo Province there is a paucity of data which this study aimed to quantify and characterise the severe trauma burden in the province.
Methods: A retrospective chart review for all patients with injury severity score (ISS) > 16 over a 6-year period (Jan 2015-Dec 2020) at two central hospitals in Limpopo province.
Variations in Neuromuscular Functions After Platelet-Rich Plasma and Dextrose Injections in Chronic Lateral Epicondylitis: A Randomized Controlled Study.
Sports Health
January 2025
Institute of Allied Health Sciences, College of Medicine, National Cheng-Kung University, Tainan, Taiwan.
Background: Lateral epicondylitis is caused by overuse and manifests as pain, weakness, and difficulty with object manipulation. Platelet-rich plasma (PRP) and dextrose injections have shown promise in reducing pain and improving function.
Hypothesis: PRP is more effective for force precision control of the extensor carpi radialis brevis (ECRB) muscle than dextrose injection for patients with chronic lateral epicondylitis (CLE).
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