Aging brains that share many cognitive deficits with the early stages of Alzheimer's-type dementias are not caused by toxic protein deposits but by somatic mutations that impair synaptic signaling. These mutant proteins that contribute to neuronal action potentials could be biomarkers of functional defects that offer new approaches to diagnosis and treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1096/fj.202301255RR | DOI Listing |
Publication Analysis
Top Keywords
impaired electrical
4
electrical activity
4
activity brain
4
brain explains
4
explains onset
4
onset dementia
4
dementia aging
4
aging people
4
people aging
4
aging brains
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!