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An Integrated Method for Crafting Flexible and Convenient Electrophysiological Optrodes for Multi-Region In Vivo Recording.
J Vis Exp
November 2024
State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University;
Epilepsy is a neurological disorder characterized by synchronized abnormal discharges involving multiple brain regions. Focal lesions facilitate the propagation of epileptic signals through associated neural circuits. Therefore, in vivo recording of local field potential (LFP) from the critical brain regions is essential for deciphering the circuits involved in seizure propagation.
View Article and Find Full Text PDFDepth versus surface: A critical review of subdural and depth electrodes in intracranial electroencephalographic studies.
Epilepsia
July 2024
Department of Neurology, University of Chicago, Chicago, Illinois, USA.
Article Synopsis
- Intracranial electroencephalographic (IEEG) recording using subdural electrodes (SDEs) and stereoelectroencephalography (SEEG) is essential for identifying the epileptogenic zone responsible for seizures.
- SDEs are better for mapping surface seizure activity while SEEG allows for deeper brain exploration, with SEEG being associated with fewer complications and better overall tolerance.
- The combination of both techniques may enhance the accuracy of seizure localization, and recent studies provide insights into when to use each method effectively in clinical practice.
Further insights into afterdischarges as a diagnostic marker for myotonic dystrophy type 1.
Neurol Sci
February 2024
Department of Neurology, Dongsan Hospital, Keimyung University School of Medicine, 1035 Dalgubeol-Daero, Dalseo-Gu, Daegu, 42601, Republic of Korea.
The Dostoyevsky effect: epileptogenesis and memory enhancement after kindling stimulation in the primate basolateral amygdala.
Annu Int Conf IEEE Eng Med Biol Soc
November 2021
Kindling is an electrical stimulation technique used to lower the threshold for epileptogenic activity in the brain. It can also be used as a tool to investigate electrophysiologic alterations that occur as a result of seizures. Epileptiform activity, like seizures and after-discharges (AD; evoked epileptiform activity), commonly cause memory impairment but rarely, can elicit vivid memory retrieval.
View Article and Find Full Text PDFAfter-discharge in the upper airway muscle genioglossus following brief hypoxia.
Sleep
September 2021
Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, Australia.
Study Objectives: Genioglossus (GG) after-discharge is thought to protect against pharyngeal collapse by minimizing periods of low upper airway muscle activity. How GG after-discharge occurs and which single motor units (SMUs) are responsible for the phenomenon are unknown. The aim of this study was to investigate genioglossal after-discharge.
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