Polysaccharides originating from marine sources have been studied as potential material for use in wound dressings because of their desirable characteristics of biocompatibility, biodegradability, and low toxicity. Marine-derived polysaccharides used as wound dressing, provide several benefits such as promoting wound healing by providing a moist environment that facilitates cell migration and proliferation. They can also act as a barrier against external contaminants and provide a protective layer to prevent further damage to the wound. Research studies have shown that marine-derived polysaccharides can be used to develop different types of wound dressings such as hydrogels, films, and fibres. These dressings can be personalised to meet specific requirements based on the type and severity of the wound. For instance, hydrogels can be used for deep wounds to provide a moist environment, while films can be used for superficial wounds to provide a protective barrier. Additionally, these polysaccharides can be modified to improve their properties, such as enhancing their mechanical strength or increasing their ability to release bioactive molecules that can promote wound healing. Overall, marine-derived polysaccharides show great promise for developing effective and safe wound dressings for various wound types.
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http://dx.doi.org/10.1016/j.ijbiomac.2023.127331 | DOI Listing |
Int J Biol Macromol
January 2025
Department of Food Science, Shenyang Medical college, Shenyang, Liao Ning 110034, PR China. Electronic address:
Sulfated polysaccharides refer to polysaccharides containing sulfate groups on sugar units. In nature, sulfated polysaccharides are widely distributed in marine organisms, and the variation in sulfation sites, monosaccharide composition, and branched chain distribution among different species results in differences in the physicochemical properties and biological activities. From the latest perspective, this review summarized the types, structural characteristics, and potential health benefits of sulfated polysaccharides in marine foods.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders, Institute of Brain Science and Disease, Qingdao University, Qingdao, China.
Neurodegenerative diseases are primarily characterized by the selective loss of neurons in the brain, leading to a significant and widespread global public health burden. Although numerous mechanisms underlying neurodegenerative diseases have been elucidated, effective therapeutic strategies are still being explored. Several drugs have been proposed to halt disease progression; however, they often come with severe side effects.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Material Science and Engineering, Huaqiao University, Engineering Research Center of Environment-Friendly Functional Materials, Ministry of Education, Xiamen 361021, PR China. Electronic address:
Osteosarcoma is a highly aggressive tumor that originates in the bone and often infiltrates nearby bone cells. It is the most prevalent type of primary bone cancer among the various bone malignancies. Traditional cancer treatment methods such as surgery, chemotherapy, immunotherapy, and radiotherapy have had restricted success.
View Article and Find Full Text PDFFoods
November 2024
College of Life Sciences, Qingdao University, Qingdao 266071, China.
In recent years, research on active polysaccharides has progressed significantly, particularly regarding their anticancer and immunomodulatory properties. Among these, clam polysaccharides, a type of marine-derived polysaccharide, exhibit notable biological activities, including both anticancer effects and immune modulation. The aims of this study are to investigate the anticancer and immunomodulatory effects of microwave-extracted clam polysaccharide (MCP) in vitro.
View Article and Find Full Text PDFMar Drugs
November 2024
Department of Pharmacological and Biomolecular Sciences, 'Rodolfo Paoletti', Via Balzaretti 9, Università degli Studi di Milano, 20133 Milano, Italy.
Cardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is the dominant cause of CVDs, and its risk factors are elevated levels of low-density lipoprotein cholesterol and triglycerides, hypertension, cigarette smoking, obesity, and diabetes mellitus. In addition, diverse evidence highlights the role played by inflammation and clonal haematopoiesis, eventually leading to immunity involvement.
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