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Cutaneous Intertriginous Langerhans Cell Histiocytosis in Adults: A Case Report and Systematic Review.
J Low Genit Tract Dis
January 2025
Saint Louis University School of Medicine, St. Louis, MO.
Objective: Authors characterized all published adult cases of cutaneous, intertriginous Langerhans cell histiocytosis (LCH) to bring this clinical presentation to the attention of clinicians. We emphasize the morphology, histopathology, immunohistochemical profiles, and genetic mutations associated with these cases.
Materials And Methods: A systematic review of the National Center for Biotechnology Information's PubMed was conducted, utilizing the following specific key words to identify all adult LCH patients with cutaneous intertriginous involvement: "Intertriginous Langerhans," "Vulvar Langerhans," "Genital Langerhans," "Perineal Langerhans," "Perianal Langerhans," "Intergluteal Langerhans," "Inguinal Langerhans," "Axillary Langerhans," and "Inframammary Langerhans.
Estimating the Benefit of Transplant Over Dialysis in Candidates Over 55 Years.
Kidney360
January 2025
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, CA.
Background: 'Life Years from Transplant' (LYFT) is a measure of the predicted difference between the expected lifespan with and without a kidney transplant. The metric was originally proposed in 1999; since then, demographics of the kidney transplant candidate population have materially changed.
Methods: Using contemporary SRTR data, we propose more sophisticated methods for estimating LYFT with a focus on older kidney transplant candidates, a growing sector of the current candidate pool.
The Impact of International Fellowship on Research Productivity: International Fellowship on Research Productivity.
Ann Plast Surg
February 2025
From the Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN.
International medical graduates (IMGs) represent a significant portion of the US physician workforce, comprising 25% across all specialties with a strong presence in internal medicine and primary care. However, their representation in plastic surgery remains limited at only 10%. Matching into a US plastic surgery residency is highly competitive for both US medical graduates and IMGs.
View Article and Find Full Text PDF50 Years of the Journal of the Brazilian College of Surgeons: History, Evolution and Future Prospects.
Rev Col Bras Cir
January 2025
- Universidade Federal de Sao Paulo, Escola Paulista de Medicina - São Paulo - SP - Brasil.
This article celebrates the 50th anniversary of the continuous publication of the Journal of the Brazilian College of Surgeons (RCBC), revisiting its trajectory from the beginning to the present day. RCBC has evolved from a nationally relevant publication to a journal with international impact, constantly adapting to changes in editorial and scientific practices. This article presents an analysis of the major milestones, editorial changes, and innovations that have cemented RCBC as a prominent scientific vehicle.
View Article and Find Full Text PDFHealthcare resource utilization and costs of using Cariprazine as the first versus subsequent adjunctive therapy for major depressive disorder.
J Med Econ
January 2025
AbbVie, North Chicago, IL, USA.
Aim: Inadequate response to antidepressant therapy (ADT) is common in major depressive disorder (MDD); atypical antipsychotic (AA) adjunctive therapy may be effective for these patients. This study aimed to compare healthcare resource utilization (HRU) and costs between patients initiating the AA cariprazine as their first adjunctive therapy vs those initiating cariprazine subsequently.
Methods: The Merative MarketScan® Commercial Database (January 1, 2015, to June 30, 2021) was used to identify US adults with MDD and ≥1 pharmacy claim for cariprazine adjunctive to ADT in 2018 or after.
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