AI Article Synopsis

  • The article discusses a correction related to a previous study on using Rhodium(II) as a catalyst for adding fluorinated alkyl groups to indole structures.
  • It highlights the importance of this transannulation method in organic synthesis and its potential applications in pharmaceuticals.
  • The correction addresses specific errors in the original publication, ensuring accurate scientific communication and improving the research integrity.

Article Abstract

Correction for 'Rhodium(II)-catalyzed transannulation approach to -fluoroalkylated indoles' by Olga Bakhanovich , , 2023, https://doi.org/10.1039/d3ob01415k.

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http://dx.doi.org/10.1039/d3ob90145aDOI Listing

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Article Synopsis
  • The article discusses a correction related to a previous study on using Rhodium(II) as a catalyst for adding fluorinated alkyl groups to indole structures.
  • It highlights the importance of this transannulation method in organic synthesis and its potential applications in pharmaceuticals.
  • The correction addresses specific errors in the original publication, ensuring accurate scientific communication and improving the research integrity.
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Copper(I)-catalyzed cycloaddition of substituted cyclohexenyl acetylenes with azido(per)fluoroalkanes afforded 4-cyclohexenyl-substituted -(per)fluoroalkylated 1,2,3-triazoles. Their rhodium(II)-catalyzed transannulation led to fused -(per)fluoroalkyl pyrroles and subsequent oxidation provided -(per)fluoroalkyl indoles.

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Medium-sized heterocycles exist in a broad spectrum of biologically active natural products and medicinally important synthetic compounds. The construction of medium-sized rings remains challenging, particularly the assembly of different ring sizes from the same type of substrate. Here we report palladium-catalyzed, regiodivergent [5 + 4] and [5 + 2] annulations of vinylethylene carbonates and allylidenemalononitriles.

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