This work presents Chameleon, a cloud computing (CC) Industry 4.0 (I4) neutron spectrum unfolding code. The code was designed under the Python programming language, using Streamlit framework®, and it is executed on the cloud, as I4 CC technology through internet, by using mobile devices with internet connectivity and a web navigator. In its first version, as a proof of concept, the SPUNIT algorithm was implemented. The main functionalities and the preliminary tests performed to validate the code are presented. Chameleon solves the neutron spectrum unfolding problem and it is easy, friendly and intuitive. It can be applied with success in various workplaces. More validation tests are in progress. Future implementations will include improving the graphical user interface, inserting other algorithms, such as GRAVEL, MAXED and neural networks, and implementing an algorithm to estimate uncertainties in the calculated integral quantities.
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http://dx.doi.org/10.1093/rpd/ncac298 | DOI Listing |
Rev Sci Instrum
December 2024
Commonwealth Fusion Systems, Devens, Massachusetts 01434, USA.
The spectrum of neutrons emitted by thermonuclear plasmas encodes information about the fuel ion distribution function. Measuring these fast neutron spectra with sufficient resolution allows for the measurement of plasma properties such as the ion temperature and strength and energy of fast ion populations. Liquid organic scintillators are a commonly used fast neutron detection technology because of their high detection efficiency and ability to discriminate between neutrons and gammas.
View Article and Find Full Text PDFSci Rep
December 2024
Sandia National Laboratories, Livermore, CA, 94550, USA.
Energy-resolved fast-neutron radiography is a powerful non-destructive technique that can be used to remotely measure the quantity and distribution of elements and isotopes in a sample. This is done by comparing the energy-dependent neutron transmission of a sample with the known cross-sections of individual isotopes. The reconstruction of the composition is possible due to the unique features (e.
View Article and Find Full Text PDFHeliyon
October 2024
Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute, AEOI, Iran.
A radiation shield consists of borated polyethylene (7 % wt of boron) and lead was used for the HPGe detector in Isfahan MNSR's PGNAA facility in order to remove scattered neutrons and gamma rays, respectively. Therefore, the boron peak in gamma spectroscopy is related to both resources in the sample and in the shield, and it has caused a challenge in determination of boron concentration in the samples. In this research, various methods have been investigated to remove the effect of boron in the shield of the detector.
View Article and Find Full Text PDFJ Colloid Interface Sci
March 2025
Biological Physics Laboratory, Department of Physics and Astronomy, School of Natural Science, The University of Manchester, Oxford Road, Manchester M13 9PL UK. Electronic address:
Antimicrobial resistance (AMR) is fast becoming a major global challenge in both hospital and community settings as many current antibiotics and treatment processes are under the threat of being rendered less effective or ineffective. Synergistic combination of an antibiotic and an aiding agent with a different set of properties provides an important but largely unexploited option to 'repurpose' existing biomaterial's space while addressing issues of potency, spectrum, toxicity and resistance in early stages of antimicrobial drug discovery. This work explores how to combine tetracycline/minocycline (TC/MC) with a broad-spectrum antimicrobial lipopeptide that has been designed to improve the efficiency of membrane targeting and intramembrane accumulation, thereby enhancing antimicrobial efficacy.
View Article and Find Full Text PDFBioorg Chem
November 2024
Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, Shenzhen Grubbs Institute and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen 518000, China. Electronic address:
3CL is crucial to the life cycle of SARS-CoV-2 and exhibits high sequence similarity with other coronaviruses, while being absent in human proteases. This makes it an ideal target for developing broad-spectrum antiviral drugs. Ensitrelvir (S-217622) is the only launched non-covalent, non-peptidomimetic 3CL inhibitor, offering certain advantages in terms of dosage and metabolism.
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