uses numerous strategies to survive and persist in the intracellular environment of professional phagocytes, including modulation of the SUMOylation process. This study aims to understand how alters host SUMOylation to enhance its intracellular survival in professional phagocytes. Our results indicate that strain Newman utilizes PtpA-driven phosphorylation to decrease the amount of SUMOylated proteins in murine macrophages to facilitate its survival in this immune cell type.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10714793PMC
http://dx.doi.org/10.1128/spectrum.02813-23DOI Listing

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