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| http://dx.doi.org/10.1186/s12978-023-01683-z | DOI Listing |
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Changes in blood biomarkers correlate with changes in cardiac size and function in patients with tetralogy of Fallot.
Int J Cardiol Congenit Heart Dis
September 2024
Erasmus University Medical Center, Department of Pediatrics, Division of Pediatric Cardiology, Rotterdam, the Netherlands.
Introduction: Patients after surgical correction of Tetralogy of Fallot (ToF) often show adverse cardiac remodeling. To better understand the underlying biological processes, we studied the relation between changes in blood biomarkers and changes in biventricular size and function as assessed by cardiac magnetic resonance imaging (CMR).
Methods: This study included 50 ToF patients, who underwent blood biomarker and CMR analysis at least twice between 2002 and 2018.
Employment of a Newly Defined In Vitro Fertilization Protocol to Determine the Cytoskeletal Machinery, DNA Damage, and Subsequent DNA Repair Resulting from Endocrine Disruption by Hexavalent Chromium in Rat Metaphase II Oocytes.
Curr Protoc
December 2024
Department of Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas.
These protocols describe a detailed method to determine the DNA damage and F-actin and microtubule defects of metaphase II oocytes caused by hexavalent chromium, Cr(VI), an endocrine disrupting chemical (EDC). The protocol provides systematic steps to determine protein expression encoded by pluripotency proteins such as Oct4, Nanog, and Cdx2 during early embryonic development. Occupational or environmental exposure to EDCs has significantly increased infertility in both men and women.
View Article and Find Full Text PDFWater Oxidation in the Presence of Iron-Doped Copper (Hydr)Oxide.
Inorg Chem
December 2024
Department of Chemistry, Sharif University of Technology, Tehran 11155-9516, Iran.
This study explores the influence of Fe ion incorporation on the oxygen-evolution reaction (OER) in alkaline media, utilizing CuO-based materials. Instead of developing an efficient and stable OER catalyst, this research investigates two distinct CuO variants: one with Fe ions adhered to the surface and another with Fe ions integrated into the CuO lattice. By employing a variety of analytical techniques, the study demonstrates that the CuO variant with surface-bound Fe ions (referred to as compound 1) exhibits significantly enhanced OER performance compared to the variant with internally embedded Fe ions (referred to as compound 2).
View Article and Find Full Text PDFSex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
Alzheimers Dement
December 2024
Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Introduction: The effects of sex and apolipoprotein E (APOE)-Alzheimer's disease (AD) risk factors-on white matter microstructure are not well characterized.
Methods: Diffusion magnetic resonance imaging data from nine well-established longitudinal cohorts of aging were free water (FW)-corrected and harmonized. This dataset included 4741 participants (age = 73.
Isolated Corrective Saccades in the Bilateral Posterior Canal Stimulation During the Video Head Impulse Test: A Marker of Central Vestibulopathy?
Ear Hear
December 2024
Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Objectives: This study aimed to determine if the presence of corrective saccades during video head impulse test (vHIT) stimulation of the bilateral posterior semicircular canals (PSCs) correlated with other vestibular test results, demographics, symptoms, or diagnoses.
Design: This study was a retrospective chart review where 1006 subjects' vHIT records were screened with 17 subjects meeting inclusion criteria for isolated bilateral PSC saccades.
Results: Of the 1006 patients undergoing vHIT testing, only 1.
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