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http://dx.doi.org/10.14336/AD.2023.0819 | DOI Listing |
Adv Rheumatol
January 2025
Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Background: Endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are adaptive mechanisms for conditions of high protein demand, marked by an accumulation of misfolded proteins in the endoplasmic reticulum (ER). Rheumatic autoimmune diseases (RAD) are known to be associated with chronic inflammation and an ERS state. However, the activation of UPR signaling pathways is not completely understood in Sjögren's disease (SD).
View Article and Find Full Text PDFSci Rep
January 2025
Department of Psychology, Division of Neuropsychology, University of Constance, Fach 905, Universitaetsstrasse 10, 78464, Constance, Germany.
Adverse early-life experiences alter the regulation of major stress systems such as the hypothalamic-pituitary-adrenal (HPA) axis. Low early-life maternal care (MC) has repeatedly been related to blunted cortisol stress responses. Likewise, an acutely increased awareness of mortality (mortality salience [MS]) also has been shown to blunt cortisol responses.
View Article and Find Full Text PDFInt J Pharm
January 2025
UniSA: Clinical & Health Sciences, University of South Australia, Adelaide, Australia. Electronic address:
Decreased saliva production due to salivary gland damage can result in difficulty speaking and swallowing, significantly reducing quality of life for head and neck cancer patients receiving radiotherapy. It is therefore imperative that treatment options are available to mitigate the effects of these debilitating side effects. D-limonene, a naturally occurring terpene, has shown protective effects on saliva production during radiotherapy treatment of mice, however the lipophilic nature of the molecule has necessitated a high oral dose to facilitate sufficient absorption.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Otolaryngology Department, İzmir Bozyaka Training and Research Hospital, İzmir City Hospital, Bahar, Saim Çıkrıkçı Cd. No: 59, 35170 Karabağlar, Izmir, Turkey.
Sialolithiasis is a common cause of salivary gland obstruction, leading to symptoms such as pain and swelling. In cases of intraparenchymal submandibular stones and proximal ductal stones larger than 7 mm, interventional sialendoscopy may fail, necessitating sialoadenectomy. As an alternative, intraoral stone extraction can be performed with CT-guided navigation.
View Article and Find Full Text PDFAm J Dent
December 2024
Department of Prosthodontics and Periodontics, University of São Paulo (USP), Bauru, Brazil,
Purpose: This mini-review discusses the clinical implication of respiratory pathogens in the biofilm on acrylic resin removable dentures in the elderly.
Methods: A search was conducted using the keywords: "dentures", " acrylic resin", "biofilm", "pneumonia", "elderly", "respiratory pathogens", and "respiratory diseases" in databases PubMed/Medline, Lilacs, SciELO and textbooks between 1999 and 2024.
Results: The elderly are more susceptible to chronic diseases and/or life-threatening infections because of senescence itself and functional and degenerative alterations.
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