Children who undergo ileal pouch anal anastomosis (IPAA) surgery for refractory ulcerative colitis (UC) may ultimately develop a Crohn's disease (CD) phenotype. This de novo CD is open to broad interpretation and misattribution, and its manifestation in children is poorly understood. The surgically altered environment of the ileal pouch is at risk of a spectrum of ileal pouch disorders, which have limited description in children. In this issue of Inflammatory Bowel Diseases, a multicenter, retrospective study of children with UC who underwent IPAA and developed de novo CD highlights the challenges and opportunities of ileal pouch characterization in children.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/ibd/izad231 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Risk of cancer and reoperation after ileorectal anastomosis and ileal pouch-anal anastomosis in familial adenomatous polyposis.
Am J Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Objectives: To prevent colorectal cancer (CRC), most patients with familial adenomatous polyposis (FAP) undergo (procto)colectomy with ileorectal anastomosis (IRA) or ileal pouch-anal anastomosis (IPAA). After surgery, these patients remain at risk of developing cancer in the remnant rectum or rectal cuff/pouch. We aimed to compare the long-term risk of cancer following IRA or IPAA in FAP.
View Article and Find Full Text PDFFecal Microbiota Transplantation for Chronic Pouchitis: A Systematic Review and Meta-Analysis.
Microorganisms
November 2024
Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Creighton University, Omaha, NE 68178, USA.
Pouchitis is a common complication after ileal-pouch anal anastomosis in patients with medically refractory ulcerative colitis. There has been a lack of high-level evidence focusing on the safety and efficacy outcomes of fecal microbiota transplantation (FMT). We aim to evaluate outcomes and complications of fecal microbiota transplantation (FMT) for chronic pouchitis.
View Article and Find Full Text PDFEffect of obesity on postoperative complications in ulcerative colitis: A systematic review and meta-analysis.
Ann Gastroenterol Surg
January 2025
Department of Surgery, Transplantation and Gastroenterology Semmelweis University Budapest Hungary.
Article Synopsis
- The study investigates the impact of obesity on postoperative complications in ulcerative colitis patients undergoing a specific surgery (IPAA).
- Results showed no significant difference in overall complication rates between obese and non-obese patients, though obese patients had slightly longer hospital stays.
- The findings highlight low certainty of evidence, suggesting further research is needed to draw definitive conclusions.
Ileal Pouch-Anal Anastomosis for Ulcerative Colitis: Predictors of Early and Late Complications.
Cureus
December 2024
Department of Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, IND.
Background Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is often considered the preferred surgical treatment for ulcerative colitis. This study was conducted to investigate the early and late complications of ileal pouch-anal anastomosis in patients with ulcerative colitis, as well as the factors associated with these complications. Methodology All relevant clinical and operative data of patients (n = 101) who underwent IPAA for ulcerative colitis between January 1995 and December 2018 were retrieved from a prospectively maintained database.
View Article and Find Full Text PDFRevisional Surgery Due to Weight Regain or Insufficient Weight Loss Following One Anastomosis Gastric Bypass.
Cureus
November 2024
Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, ISR.
Introduction: One anastomosis gastric bypass (OAGB) is a common procedure associated with satisfactory outcomes. Revisional surgery due to weight regain or insufficient weight loss (WR/IWL) after OAGB is underreported.
Methods: A retrospective analysis of a single-bariatric surgeon database was conducted.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!